Logic Synthesis for Genetic Diseases

Modeling Disease Behavior Using Boolean Networks

Authors: Lin, Pey-Chang Kent, Khatri, Sunil P.

  • Discusses a new application for logic synthesis, which enables the use of Boolean Networks to model the behavior of genetic-based diseases
  • Demonstrates how techniques such as Boolean Satisfiability (SAT) and Automatic Test Pattern Generation (ATPG) can be applied in the context of genetics
  • Provides content that appeals to researchers in genetics and logic synthesis and enables readers to make the connection between genetic diseases and logic techniques in a clear, unambiguous manner
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  • ISBN 978-1-4614-9429-4
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  • ISBN 978-1-4614-9428-7
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Softcover $129.00
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  • ISBN 978-1-4939-5535-0
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  • Usually dispatched within 3 to 5 business days.
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About this book

This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful implicit enumeration techniques. Coverage also includes techniques from VLSI testing to control a faulty BN, transforming its behavior to a healthy BN, potentially aiding in efforts to find the best candidates for treatment of genetic diseases.

Table of contents (6 chapters)

  • Introduction

    Lin, Pey-Chang Kent (et al.)

    Pages 1-21

  • Predictor Set Inference using SAT

    Lin, Pey-Chang Kent (et al.)

    Pages 25-38

  • Determining Gene Function in Boolean Networks using SAT

    Lin, Pey-Chang Kent (et al.)

    Pages 39-51

  • Predictor Ranking using Modified Zhegalkin Functions

    Lin, Pey-Chang Kent (et al.)

    Pages 53-74

  • ATPG for Cancer Therapy

    Lin, Pey-Chang Kent (et al.)

    Pages 77-92

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-1-4614-9429-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA
  • ISBN 978-1-4614-9428-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
price for USA
  • ISBN 978-1-4939-5535-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Logic Synthesis for Genetic Diseases
Book Subtitle
Modeling Disease Behavior Using Boolean Networks
Authors
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-9429-4
DOI
10.1007/978-1-4614-9429-4
Hardcover ISBN
978-1-4614-9428-7
Softcover ISBN
978-1-4939-5535-0
Edition Number
1
Number of Pages
XXI, 100
Number of Illustrations and Tables
20 b/w illustrations, 8 illustrations in colour
Topics