Advances in Biochemistry in Health and Disease

Proteases in Health and Disease

Editors: Chakraborti, Sajal, Dhalla, Naranjan S. (Eds.)

  • First volume to comprehensively explore the role of proteases in various diseases
  • Provides information on the pathogenesis of cellular dysfunction, with strong emphasis on identifying proteases and their endogenous inhibitors as targets for drug development
  • Utilizes a multidisciplinary approach to biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases​
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-4614-9233-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4614-9232-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-4853-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In view of rapidly growing research in the deregulation of proteases and their impact in human health and diseases, this book will highlight existing and emerging research in this exciting area. In-depth critical state-of-the-art reviews will be written by established investigators on proteases dysfunctions associated with pathogenesis of different diseases that are known to occur due to deregulation of proteolytic systems. Multidisciplinary approaches demonstrating biochemical and signal transduction mechanisms associated with deregulation of proteases leading to manifestation of the diseases will be discussed. The book highlights the roles of both intracellular and extracellular proteases in health and disease.

About the authors

Dr. Sajal Chakraborti is a Senior Professor of Biochemistry at the University of Kalyani, West Bengal, India. His research covers the role of proteases in regulating pulmonary vascular tone under oxidant- and calcium-signaling phenomena. He has been engaged in teaching and research in biochemistry for the past 35 years.

Dr. Naranjan Dhalla is a Distinguished Professor at the University of Manitoba, Winnipeg, Canada. His expertise includes the subcellular and molecular basis of heart function in health and disease. He has been engaged in multidisciplinary research and education for promoting the scientific basis of cardiology, as well as training of professional manpower for combating heart disease for over 40 years.

Table of contents (22 chapters)

  • An Overview of Endoplasmic Reticulum Calpain System

    Samanta, Krishna (et al.)

    Pages 3-19

  • Mitochondrial Calpains: Who, What, Where, When and Why?

    Geddes, James W.

    Pages 21-32

  • Role of Calpains in Calmodulin Regulated Systems

    Parameswaran, Sreejit (et al.)

    Pages 33-48

  • Exercise and Matrix Metalloproteases in Health and Disease: A Brief Overview

    Shaikh, Soni (et al.)

    Pages 49-62

  • Regulation of Chondrocyte Matrix Metalloproteinase Gene Expression

    Malemud, Charles J.

    Pages 63-77

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4614-9233-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4614-9232-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-4853-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Proteases in Health and Disease
Editors
  • Sajal Chakraborti
  • Naranjan S. Dhalla
Series Title
Advances in Biochemistry in Health and Disease
Series Volume
7
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-9233-7
DOI
10.1007/978-1-4614-9233-7
Hardcover ISBN
978-1-4614-9232-0
Softcover ISBN
978-1-4939-4853-6
Edition Number
1
Number of Pages
XV, 403
Number of Illustrations and Tables
47 b/w illustrations, 37 illustrations in colour
Topics