Nanomedicine and Nanotoxicology

Nanotoxicology

Materials, Methodologies, and Assessments

Editors: Durán, Nelson, Guterres, Silvia S., Alves, Oswaldo Luiz (Eds.)

  • Provides an introduction to nanostructures actually in use
  • Describes cyto- and genotoxicity methodologies, and assesses their performance in comparison to common toxicity assays
  • Discusses the relation of cytotoxicity and genotoxicity to ecotoxicity
  • Presents a range of applications, from biogenic silver nanoparticles to poloxamers as drug-delivery systems, reflecting the expanding applications of nanotechnology
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Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-1-4614-8993-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-1-4614-8992-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4939-4793-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book takes a systematic approach to nanotoxicology and the developing risk factors associated with  nanosized particles during manufacture and use of nanotechnology. Beginning with a detailed introduction to engineered nanostructures, the first part of the book presents concepts and definitions of nanomaterials from quantum dots to graphene to fullerenes, with detailed discussion of functionalization, stability, and medical and biological applications. The second part critically examines methodologies used to assess cytotoxicity and genotoxicity. Coverage includes interactions with blood (erythrocytes), combinatorial and microarray techniques, cellular mechanisms, and ecotoxicology assessments. Part three describes cases studies both in vitro and in vivo for specific nanomaterials including solid lipid nanoparticles and nanostructured lipid carriers and metallic nanoparticles and metallic oxides. New information is also presented on toxicological aspects of poloxamers and polymeric nanoparticles as drug carriers as well as size effects on cytotoxicity and genotoxicity. Didactic aspects are emphasized in all chapters, making the book suitable for a broad audience ranging from advanced undergraduate and graduate students to researchers in academia and industry. In all, Nanotoxicology: Materials, Methodologies, and Assessments will provide comprehensive insight into biological and environmental interactions with nanostructures.

  • Provides an introduction to nanostructures actually in use
  • Describes cyto- and genotoxicity methodologies, and assesses their performance in comparison to common toxicity assays
  • Discusses the relation of cytotoxicity and genotoxicity to ecotoxicity
  • Presents a range of applications, from biogenic silver nanoparticles to poloxamers as drug-delivery systems, reflecting the expanding applications of nanotechnology

Table of contents (17 chapters)

  • Nanomaterials

    Alves, Oswaldo L. (et al.)

    Pages 1-29

  • Concepts and Methodology of Interaction of Carbon Nanostructures with Cellular Systems

    Oliveira, Alexandre L. R. (et al.)

    Pages 31-55

  • Nanostability

    Cauerhff, Ana (et al.)

    Pages 57-95

  • Pharmacokinetics and Pharmacodynamics of Nanomaterials

    Marcato, Priscyla D.

    Pages 97-110

  • In Vitro Cytotoxicity Assays of Nanoparticles on Different Cell Lines

    Melo, Patricia S. (et al.)

    Pages 111-123

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-1-4614-8993-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-1-4614-8992-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4939-4793-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Nanotoxicology
Book Subtitle
Materials, Methodologies, and Assessments
Editors
  • Nelson Durán
  • Silvia S. Guterres
  • Oswaldo Luiz Alves
Series Title
Nanomedicine and Nanotoxicology
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
Distribution Rights
Distribution rights for India: Delhi Book Store, New Delhi, India
eBook ISBN
978-1-4614-8993-1
DOI
10.1007/978-1-4614-8993-1
Hardcover ISBN
978-1-4614-8992-4
Softcover ISBN
978-1-4939-4793-5
Series ISSN
2194-0452
Edition Number
1
Number of Pages
XV, 411
Number of Illustrations and Tables
20 b/w illustrations, 22 illustrations in colour
Topics