Biophysics for the Life Sciences

Molecular Biophysics for the Life Sciences

Editors: Allewell, Norma M., Narhi, Linda O., Rayment, Ivan (Eds.)

  • Provides an overview of major research themes and research strategies in contemporary molecular biophysics
  • Introduces new investigators to major areas of biophysics
  • Explains the goals of biophysical research, while offering the tools available for investigation, the relevance of biological research to other fields, and future opportunities in the field
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eBook $99.00
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  • ISBN 978-1-4614-8548-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
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  • Immediate eBook download after purchase
Hardcover $129.00
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  • ISBN 978-1-4614-8547-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
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  • ISBN 978-1-4939-4242-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution.   It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions.  Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions. 

About the authors

Dr. Norma M. Allewell is Professor of Cell Biology and Molecular Genetics and Affiliate Professor of Chemistry and Biochemistry at the University of Maryland, where she served as Dean of the College of Chemical and Life Sciences for a decade. Her research focuses on protein structure, function and dynamics, and metabolic regulatory mechanisms and diseases.

Dr. Linda Narhi is a Scientific Executive Director in the Product Attribute Science Group at Amgen, where her responsibilities include solution stability assessment of all protein-based therapeutic candidates, and developing and implementing predictive assays for protein stability to process, storage, and delivery conditions.

Dr. Ivan Rayment is Professor of Biochemistry at the University of Wisconsin-Madison, where he holds the Michael G. Rossmann Professorship in Biochemistry. He has a wide range of interests in structural biology and has made seminal contributions to our understanding of the structural basis of motility, enzyme evolution, cobalamin biosynthesis, and transposition.

Reviews

From the reviews:

“This valuable work describes the major methods used for characterizing biological macromolecules. The book is very readable and well organized, with 12 succinct chapters. … Summing Up: Highly recommended. Upper-division undergraduates and above.” (J. A. Kelly, Choice, Vol. 51 (10), June, 2014)

Table of contents (12 chapters)

  • Introduction

    Allewell, Norma M. (et al.)

    Pages 1-15

  • Structural, Physical, and Chemical Principles

    Allewell, Norma M. (et al.)

    Pages 17-30

  • Optical Spectroscopic Methods for the Analysis of Biological Macromolecules

    Narhi, Linda O. (et al.)

    Pages 33-90

  • Diffraction and Scattering by X-Rays and Neutrons

    Rayment, Ivan

    Pages 91-112

  • Nuclear Magnetic Resonance Spectroscopy

    Pochapsky, Thomas C. (et al.)

    Pages 113-173

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-1-4614-8548-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA
  • ISBN 978-1-4614-8547-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
price for USA
  • ISBN 978-1-4939-4242-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Biophysics for the Life Sciences
Editors
  • Norma M. Allewell
  • Linda O. Narhi
  • Ivan Rayment
Series Title
Biophysics for the Life Sciences
Series Volume
6
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-8548-3
DOI
10.1007/978-1-4614-8548-3
Hardcover ISBN
978-1-4614-8547-6
Softcover ISBN
978-1-4939-4242-8
Edition Number
1
Number of Pages
XII, 397
Number of Illustrations and Tables
62 b/w illustrations, 70 illustrations in colour
Topics