Molecular Pathogenesis of Colorectal Cancer

Editors: Haigis, Kevin M. (Ed.)

  • Identification and characterization of targetable oncogenic pathways in colorectal cancer
  • Discussion of the current and future prospects for targeting that pathway therapeutically
  • Emerging technologies for identifying new cancer related genes, and therefore new therapeutic targets
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-4614-8412-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4614-8411-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-4278-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.

Table of contents (12 chapters)

  • The Genetics of Colorectal Cancer

    Hankey, William (et al.)

    Pages 1-24

  • Molecular Mechanisms of Colorectal Carcinogenesis

    Roper, Jatin (et al.)

    Pages 25-65

  • The Association Between Inflammation and Colorectal Cancer

    Oliveira, Maria José (et al.)

    Pages 67-105

  • Importance of the Niche: Wnt Signaling and Stem Cell Plasticity in Intestinal Homeostasis and Disease

    Sansom, Owen J. (et al.)

    Pages 107-120

  • Mutational Activation of KRAS and BRAF in Colorectal Cancer

    Pedone, Katherine H. (et al.)

    Pages 121-156

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4614-8412-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4614-8411-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-4278-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Pathogenesis of Colorectal Cancer
Editors
  • Kevin M. Haigis
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-8412-7
DOI
10.1007/978-1-4614-8412-7
Hardcover ISBN
978-1-4614-8411-0
Softcover ISBN
978-1-4939-4278-7
Edition Number
1
Number of Pages
VIII, 316
Number of Illustrations and Tables
1 b/w illustrations, 29 illustrations in colour
Topics