Advances in Experimental Medicine and Biology

Advances in Chronic Lymphocytic Leukemia

Editors: Malek, Sami (Ed.)

  • ​Provides a comprehensive review on chronic lymphocytic leukemia
  • Features paramount research in the field
  • Focuses on crucial aspects of CLL pathogenesis
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Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4614-8051-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4614-8050-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-5389-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. CLL has a highly varied clinical course.  While advances in CLL therapy are noted, many patients still succumb to this illness. Like most progress in medicine, solid advances in the diagnosis, prognosis and treatment of CLL are rooted in an in-depth understanding of the basic and translational biology of CLL.  In this book, CLL experts have contributed state-of-the-art summaries of various important aspects of CLL biology and have discussed the translational implication of such findings.  This book, which is directed at physicians and researchers alike, aims to educate broadly and deeply.  Intentionally, the many aspects and nuances of CLL clinical care that can only really be appreciated through direct patient care are not covered here, but instead, the book presents basic aspects of CLL that underlie many of the contemporary decisions that are made in CLL research and clinical settings.

We hope that this book will critically inform the community and stimulate interest in CLL, which will ultimately translate into better CLL research, prognostication and therapy, with the end goal of providing a better outlook for patients afflicted with this common leukemia. 

About the authors

Sami N. Malek is an Associate Professor at the Department of Internal Medicine at the University of Michigan Health System. Dr. Malek's research interests include basic and translational questions in Leukemia and Lymphoma. Well known in the field of CLL, Dr. Malek is well-published in the area and is invited to international conferences and seminars to give talks on the topic.

Table of contents (14 chapters)

  • B Cell Receptor and Antigens in CLL

    Agathangelidis, Andreas (et al.)

    Pages 1-24

  • The CLL Cell Microenvironment

    Burger, Jan A.

    Pages 25-45

  • Acquired Genomic Copy Number Aberrations in CLL

    Ouillette, Peter (et al.)

    Pages 47-86

  • Recurrent Gene Mutations in CLL

    Martínez-Trillos, Alejandra (et al.)

    Pages 87-107

  • TP53 Aberrations in Chronic Lymphocytic Leukemia

    Trbusek, Martin (et al.)

    Pages 109-131

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4614-8051-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4614-8050-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4939-5389-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Advances in Chronic Lymphocytic Leukemia
Editors
  • Sami Malek
Series Title
Advances in Experimental Medicine and Biology
Series Volume
792
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-8051-8
DOI
10.1007/978-1-4614-8051-8
Hardcover ISBN
978-1-4614-8050-1
Softcover ISBN
978-1-4939-5389-9
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XI, 334
Number of Illustrations and Tables
1 b/w illustrations, 24 illustrations in colour
Topics