Cancer Drug Discovery and Development

Nuclear Signaling Pathways and Targeting Transcription in Cancer

Editors: Kumar, Rakesh (Ed.)

  • First book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade
  • Is a comprehensive look at basic and clinical science behind the functions of representative core transcriptional factors
  • Chapters are written by the leaders in their fields
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Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4614-8039-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4614-8038-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

At the moment, there is no dedicated book to summarize the roles, the significance, and potential therapeutic targeting of transcriptional factors from the perspective of signaling cascade, and thus, directly impacting the functionality of transcriptional factors in cancer. In addition, this book will offer a comprehensive basic and clinical science behind the functions of representative core transcriptional factors. These chapters will serve as a treasure for all those who have an interest in the basis, progression, and targeting of human cancer. Each chapter will be intended to provide comprehensive, up-to-date information by the leaders about the physiologic and pathologic roles of TFs in specific representative organ systems of prime importance. The book will consist of chapters that will give biomedical students, under and graduate students, basic sciences and clinical cancer fellows, residents and researchers, and oncology educators will get a thorough summary of the overall subject. The readers will be able to understand the important current information and views on specific TFs and its role in cancer in areas outside their own expertise or experience. A special emphasis will be also placed on the "classic" papers as well as perspectives on future directions for the field.

Table of contents (16 chapters)

  • Steroid Receptor Coactivators (SRCs) as Integrators of Multiple Signaling Pathways in Cancer Progression

    Long, Weiwen (et al.)

    Pages 3-32

  • Role of Alteration/Deficiency in Activation (ADA) Complex in Cell Cycle, Genomic Instability and Cancer

    Mohibi, Shakur (et al.)

    Pages 33-55

  • RUNX2 Transcriptional Regulation in Development and Disease

    Brusgard, Jessica L. (et al.)

    Pages 57-86

  • Epigenetic Mechanisms of Cancer Metastasis

    Liang, Jing (et al.)

    Pages 87-104

  • Regulatory Effects of Arsenic on Cellular Signaling Pathways: Biological Effects and Therapeutic Implications

    Beauchamp, Elspeth M. (et al.)

    Pages 107-119

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4614-8039-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4614-8038-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Nuclear Signaling Pathways and Targeting Transcription in Cancer
Editors
  • Rakesh Kumar
Series Title
Cancer Drug Discovery and Development
Copyright
2014
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-8039-6
DOI
10.1007/978-1-4614-8039-6
Hardcover ISBN
978-1-4614-8038-9
Series ISSN
2196-9906
Edition Number
1
Number of Pages
XII, 439
Topics