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Systems Biomechanics of the Cell

  • Book
  • © 2013

Overview

Authors:
  1. Ivan V. Maly

    1. Department of Computational Biology, School of Medicine, University of Pittsburgh, Pittsburgh, USA

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  • Outlines systems biomechanics of the cell as an emergent and promising discipline
  • Explores the potential to expand the spectrum of questions asked about the cell, and to further clarify the physical nature of animate matter and motion
  • Focuses on the system-level effects in the mechanics of the body, the boundary, and their interaction
  • Includes supplementary material: sn.pub/extras

Part of the book series: SpringerBriefs in Bioengineering (BRIEFSBIOENG, volume 1)

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Table of contents (1 chapter)

  1. Front Matter

    Pages i-v
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  2. Systems Biomechanics of the Cell

    • Ivan V. Maly
    Pages 1-55
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Keywords

About this book

Systems Biomechanics of the Cell attempts to outline systems biomechanics of the cell as an emergent and promising discipline. The new field owes conceptually to cell mechanics, organism-level systems biomechanics, and biology of biochemical systems. Its distinct methodology is to elucidate the structure and behavior of the cell by analyzing the unintuitive collective effects of elementary physical forces that interact within the heritable cellular framework. The problematics amenable to this approach includes the variety of cellular activities that involve the form and movement of the cell body and boundary (nucleus, centrosome, microtubules, cortex, and membrane). Among the elementary system effects in the biomechanics of the cell, instability of symmetry, emergent irreversibility, and multiperiodic dissipative motion can be noted. Research results from recent journal articles are placed in this unifying framework. It is suggested that the emergent discipline has the potential to expand the spectrum of questions asked about the cell, and to further clarify the physical nature of animate matter and motion.

Authors and Affiliations

  • Department of Computational Biology, School of Medicine, University of Pittsburgh, Pittsburgh, USA

    Ivan V. Maly

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