Current Cancer Research

Autophagy and Cancer

Editors: Wang, Hong-Gang (Ed.)

  • ​​Summarizes the key players that function in autophagosome formation, elongation and maturation​ and its involvement in cancer progression
  • Provides latest research of how autophagy is regulated
  • Explores the roles of autophagy in tumorigenesis​
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  • ISBN 978-1-4614-6561-4
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Hardcover $219.00
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  • ISBN 978-1-4614-6560-7
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Softcover $219.00
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  • ISBN 978-1-4899-9177-5
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About this book

With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it. ​

About the authors

Dr. Hong-Gang Wang is the Lois High Berstler Professor, Department of Pharmacology at Penn State College of Medicine. Dr. Wang is a leading research scientist in the area of autophagy and cancer.

Table of contents (12 chapters)

  • Historical Overview of Autophagy

    Dunn, William A. (et al.)

    Pages 1-24

  • The Core Molecular Machinery of Autophagosome Formation

    Jin, Meiyan (et al.)

    Pages 25-45

  • The Origin of Autophagosomes: The Beginning of an End

    Abreu, Susana (et al.)

    Pages 47-61

  • Signal Transduction Regulation of Autophagy

    Wong, Pui-Mun (et al.)

    Pages 63-93

  • Role of Autophagy in Tumorigenesis

    Tao, Hanlin (et al.)

    Pages 95-112

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-6561-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-6560-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-9177-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Autophagy and Cancer
Editors
  • Hong-Gang Wang
Series Title
Current Cancer Research
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-6561-4
DOI
10.1007/978-1-4614-6561-4
Hardcover ISBN
978-1-4614-6560-7
Softcover ISBN
978-1-4899-9177-5
Series ISSN
2199-2584
Edition Number
1
Number of Pages
XI, 261
Topics