Human Interphase Chromosomes

Biomedical Aspects

Editors: Yurov, Yuri B., Vorsanova, Svetlana G., Iourov, Ivan (Eds.)

  • This is the first title to review modern achievements in the field of the post-genomic era’s genomics of interphase nuclei
  • Human Interphase Chromosomes play a significant role in a variety of basic biological processes involved in realization and inheritance of genetic information within and between species​
  • Provides special attention to available molecular cytogenetic technologies for basic and clinical chromosome research
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eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-6558-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-6557-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-8539-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This title will focus on the study of human interphase chromosomes and its relation to health and disease. Orchestrated organization and human genome function in interphase nuclei at the chromosomal level have been repeatedly shown to play a significant role in a variety of basic biological processes involved in realization and inheritance of genetic information within and between species. Current biomedical sciences of post-genomic era refocus basic and applied studies of interphase nuclei genetics and genomics with special attention to interphase chromosome behavior in health and disease.   Additionally, related processes are a target of studies elucidating the role of interphase chromosome behavior during development, chromosome/DNA replication, DNA reparation etc. Studies of interphase nuclei have an appreciable impact on different areas of biomedical sciences such as cell biology, neurobiology, cancer research, developmental biology, epigenetics, cytogenetics, and medical genetics, as a whole. Moreover, development of innovative and emergent technologies to analyze  interphase nuclei are closely associated with application of these techniques in clinical, diagnostic and research practice to solve reproductive problems (including infertility and spontaneous abortions), to investigate congenital malformations (including those produced by aneuploidy and other chromosome abnormalities); genetic diseases (including cardiac, immune, neurological and psychiatric diseases), and cancer. This title will serve as a source of new valuable information and promising ideas for a wide audience of professionals in biomedicine including researchers, scientists, and healthcare professionals in human genetics, cytogenetics, and developmental biology. ​

Table of contents (11 chapters)

  • Introduction to Interphase Molecular Cytogenetics

    Yurov, Yuri B. (et al.)

    Pages 1-8

  • Interphase Chromosome Behavior in Normal and Diseased Cells

    Bourne, Gemma (et al.)

    Pages 9-33

  • Nuclear Architecture, Chromosome Aberrations, and Genetic Damage

    Folle, Gustavo A. (et al.)

    Pages 35-51

  • Interphase Chromosomes of the Human Brain: The Biological and Clinical Meaning of Neural Aneuploidy

    Iourov, Ivan Y. (et al.)

    Pages 53-83

  • Differentiating Chromosome Fragmentation and Premature Chromosome Condensation

    Stevens, Joshua B. (et al.)

    Pages 85-105

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-6558-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-6557-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-8539-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Human Interphase Chromosomes
Book Subtitle
Biomedical Aspects
Editors
  • Yuri B. Yurov
  • Svetlana G. Vorsanova
  • Ivan Iourov
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-6558-4
DOI
10.1007/978-1-4614-6558-4
Hardcover ISBN
978-1-4614-6557-7
Softcover ISBN
978-1-4899-8539-2
Edition Number
1
Number of Pages
XVII, 216
Topics