Molecular Genetics of Pancreatic Cancer

Editors: Simeone, Diane M., Maitra, Anirban (Eds.)

  • Examines the genetics of familial pancreatic cancer
  • Discusses molecularly targeted therapies in pancreatic cancer
  • Explores new technologies in molecular characterization of pancreatic cancer
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eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-6549-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-6548-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Pancreatic cancer is a formidable disease, and advances in early detection and improved therapeutics have been slow to come forth. With new advances in molecular genetics in the field of pancreatic tumorigenesis, it is an opportune time to use these recent discoveries to enhance our understanding of pancreatic cancer biology and to improve outcomes in patients. 

In this volume, leading experts in the field shed light on these findings describing the mutational landscape of pancreatic cancer, including new inroads into our understanding of familial pancreatic cancer, epidemiology, the biology of K-ras signaling, and the emerging contribution of epigenetic alterations to disease initiation and progression. The distinctive pancreatic cancer-stroma ecosystem as determined by the dynamic interplay of inflammation, hallmark mutations, EMT, and cancer stem cells is described, and implications of these interactions in the context of development of novel, personalized therapeutic options are explored.

Table of contents (10 chapters)

  • Genomic Alterations in Sporadic Pancreatic Cancer

    Molin, Marco Dal (et al.)

    Pages 1-26

  • Molecular Pathology of Pancreatic Cancer Precursor Lesions

    Brosens, Lodewijk A. A. (et al.)

    Pages 27-47

  • Genetic Epidemiology and Pancreatic Cancer

    Jiao, Li (et al.)

    Pages 49-74

  • Translational Implications of Molecular Genetics for Early Diagnosis of Pancreatic Cancer

    Hollingsworth, Michael A.

    Pages 75-82

  • The Biology of K-Ras Signaling Pathways in Pancreatic Cancer

    Court, Helen (et al.)

    Pages 83-115

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-6549-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-6548-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Genetics of Pancreatic Cancer
Editors
  • Diane M. Simeone
  • Anirban Maitra
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-6549-2
DOI
10.1007/978-1-4614-6549-2
Hardcover ISBN
978-1-4614-6548-5
Edition Number
1
Number of Pages
V, 235
Topics