Springer celebrates 175 years of publishing excellence! Join us >>

The Hippo Signaling Pathway and Cancer

Editors: Oren, Moshe, Aylon, Yael (Eds.)

  • ​Explores virtually all aspects of tumor biology in relation to the
  • Hippo Pathway
  • Gathers wide-ranging and burgeoning information into an accessible format
  • Features timely research from leading scientists in the field
see more benefits

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4614-6220-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-4614-6219-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4939-0109-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

​​The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorigenesis, and many leading scientists are showing increased interest in this growing field and it's relation to cancer.  The chapters in this volume cover virtually all aspects of tumor biology, because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Ras, Wnt, TGFbeta and p53. Moreover, Hippo signaling is not solely involved in regulating “classic” tumor characteristics such as cell proliferation, survival and growth, but is also diversely involved in cell-autonomous and non-cell-autonomous differentiation, migration and organ size control. The primary audience are researchers interested in basic science in the areas of tumor suppression, cell cycle and size regulation, development and differentiation. 

About the authors

Dr. Moshe Oren has been investigating the molecular biology of cancer-related processes for years, with particular emphasis on the p53 tumor suppressor and its associated network of proteins and genes. Dr. Oren has cloned he p53 gene when he was a post doc working under Dr. Arnold Levine. He has acted as a member of several international research consortia, as well as co-organizer of numberous national and international conferences. Dr. Oren has won several cancer research awards and his most recent achievement includes serving as President Elect of the European Association for Cancer Research in 2010. He serves on several editorial boards including Molecular Cell, EMBO Journal, Molecular and Cellular Biology, Molecular Carcinogenesis, and Molecular Oncology, to name a few.

Dr. Yael Aylon is a research associate in Dr. Oren's lab at the Weizmann Institute and has been invited to speak at several international conferences and seminar.

Table of contents (17 chapters)

  • Introduction

    Oren, Moshe (et al.)

    Pages 1-8

  • Merlin and Angiomotin in Hippo-Yap Signaling

    Yi, Chunling (et al.)

    Pages 11-25

  • MST1/2 and Other Upstream Signaling that Affect Hippo Pathway Function

    Fitamant, Julien (et al.)

    Pages 27-49

  • YAP1 Uses Its Modular Protein Domains and Conserved Sequence Motifs to Orchestrate Diverse Repertoires of Signaling

    Sudol, Marius (et al.)

    Pages 53-70

  • Regulation of YAP and TAZ Transcription Co-activators

    Yu, Fa-Xing (et al.)

    Pages 71-87

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4614-6220-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-4614-6219-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4939-0109-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
The Hippo Signaling Pathway and Cancer
Editors
  • Moshe Oren
  • Yael Aylon
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-6220-0
DOI
10.1007/978-1-4614-6220-0
Hardcover ISBN
978-1-4614-6219-4
Softcover ISBN
978-1-4939-0109-8
Edition Number
1
Number of Pages
VI, 354
Topics