Androgen-Responsive Genes in Prostate Cancer

Regulation, Function and Clinical Applications

Editors: Wang, Zhou (Ed.)

  • Focuses on androgen-responsive genes and prostate cancer, whereas other books have focused on androgen action and androgen receptors
  • Covers androgen-responsive genes in relation to carcinogenesis, cell growth, angiogenesis and more
  • Explores new approaches to diagnosis, prevention and treatment through understanding the mechanisms of androgen-responsive genes at the cellular level​  
see more benefits

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4614-6182-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-4614-6181-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4899-8687-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Androgens and androgen receptors (AR) play critical roles in the development and progression of prostate cancer, the most frequently diagnosed cancer and second leading cause of cancer death in US males.  AR is an androgen-dependent DNA-binding transcription factor that regulates the expression of androgen-responsive genes.  Identification and characterization of androgen-responsive genes provide insights into the cellular mechanisms of androgen action and may lead to new approaches in diagnosis, prognosis, prevention and/or treatment of prostate cancer.   This volume provides critical information from  well respected experts in the field.  Some of the exciting topics include the new understanding of mechanisms underlining the regulation of androgen-responsive gene expression, and functions of various androgen-responsive genes in biological processes essential in carcinogenesis including cell growth, angiogenesis, and epithelial-to-mesenchyme transition (EMT).  Other important aspects addressed are the current and potential clinic applications of knowledge on androgen-responsive gene regulation and function.  This book is intended for researchers, scientists, faculty, and advanced graduate students  with an interest in androgen action and prostate cancer.​  

About the authors

The volume editor, Dr. Zhou Wang, is well-noted in the field of prostate cancer and he is theChair for Urological Research at the University of Pittsburgh Medical Center, as well as the co-director of Urological and Prostate Cancer Program at the University of Pittsburgh Cancer Institute.He has also conducted several scientific reviews for several top journals in the area of cancer research.

Table of contents (20 chapters)

  • Roles of Androgen Receptor Coregulators and Cell Signaling in the Regulation of Androgen-Responsive Genes

    Agoulnik, Irina U. (et al.)

    Pages 1-11

  • Selective and Classical Androgen Response Elements in Androgen-Regulated Gene Expression

    Claessens, Frank (et al.)

    Pages 13-27

  • Negative Androgen-Response Elements in Androgen Target Genes

    Qi, Wei (et al.)

    Pages 29-41

  • Chromatin Looping and Long Distance Regulation by Androgen Receptor

    Sunkel, Benjamin (et al.)

    Pages 43-58

  • The Functionality of Prostate Cancer Predisposition Risk Regions Is Revealed by AR Enhancers

    Noushmehr, Houtan (et al.)

    Pages 59-84

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4614-6182-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-4614-6181-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4899-8687-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Androgen-Responsive Genes in Prostate Cancer
Book Subtitle
Regulation, Function and Clinical Applications
Editors
  • Zhou Wang
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-6182-1
DOI
10.1007/978-1-4614-6182-1
Hardcover ISBN
978-1-4614-6181-4
Softcover ISBN
978-1-4899-8687-0
Edition Number
1
Number of Pages
IX, 348
Number of Illustrations and Tables
38 b/w illustrations, 37 illustrations in colour
Topics