Advances in Experimental Medicine and Biology

The New Paradigm of Immunity to Tuberculosis

Editors: Divangahi, Maziar (Ed.)

  • Will offer a new understanding of immunity to tuberculosis
  • Explore a novel approach to designing a new tuberculosis vaccine
  • Cover the latest advances in tuberculosis research of the past decade
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eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-6111-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-6110-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-9063-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book illustrates the intimate relationship between alveolar macrophages and Mycobacterium tuberculosis (M.tb.), and the former’s role in both innate and adaptive immunity against M.tb. It covers research done over the last decade. It also explores the role of macrophage death following infection with M.tb. in determining whether successful immunity is stimulated, or whether clinical disease develops; furthermore, the function of host lipid mediators in macrophage death modality are addressed.

The book also illustrates how the balance between prostaglandins and lipoxins determines whether infected macrophages undergo apoptosis or necrosis, which is the ultimate factor in the outcome of infection.

Finally, it is a synthesis of the authors’ recent studies and the studies of others to offer a new understanding of immunity to tuberculosis.

Table of contents (14 chapters)

  • Epidemiology of Tuberculosis Immunology

    Fox, G. J. (et al.)

    Pages 1-32

  • Host–Pathogen Specificity in Tuberculosis

    Pietrantonio, Tania (et al.)

    Pages 33-44

  • Genetic Determinants of Susceptibility to Mycobacterial Infections: IRF8, A New Kid on the Block

    Salem, S. (et al.)

    Pages 45-80

  • Evolution of Mycobacterium tuberculosis

    Behr, Marcel A.

    Pages 81-91

  • Mycobacterium tuberculosis Genes Involved in Regulation of Host Cell Death

    Briken, Volker

    Pages 93-102

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-6111-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-6110-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-9063-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The New Paradigm of Immunity to Tuberculosis
Editors
  • Maziar Divangahi
Series Title
Advances in Experimental Medicine and Biology
Series Volume
783
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-6111-1
DOI
10.1007/978-1-4614-6111-1
Hardcover ISBN
978-1-4614-6110-4
Softcover ISBN
978-1-4899-9063-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VI, 292
Topics