Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems

Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems

Authors: Thiriet, Marc

  • Reviews structure and function of major constituents of the circulatory and respiratory apparatus
  • Describes major cellular processes involved in signaling, interactions, and adaptive responses of physiological conduits
  • Integrates biology, chemistry, and physics for the multidisciplinary exploration and modeling of physiological flows
  • Focuses on mechanotransduction-induced regulation
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About this book

The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models.  The resulting biomathematical models and corresponding simulation software can be incorporated into platforms developed in virtual physiology for improved understanding and training.

Table of contents (14 chapters)

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4614-5966-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4614-5965-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems
Authors
Series Title
Biomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems
Series Volume
5
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-5966-8
DOI
10.1007/978-1-4614-5966-8
Hardcover ISBN
978-1-4614-5965-1
Series ISSN
2193-1682
Edition Number
1
Number of Pages
XXI, 962
Topics