Handbook of Neurotoxicity

Editors: Kostrzewa, Richard (Ed.)

  • Guides readers through neurotoxins and neurotoxicity in Neuroscience
  • Characterizes and describes outcomes of neurotoxin treatments
  • Assists in identifying neurotoxin treatments and instructs on their use
  • Considers different manners of neuroprotection including clinical and preclinical
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About this Reference Work

The Handbook of Neurotoxicity is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.

About the authors

Dr. Kostrzewa is professor of Pharmacology. He received his BS (1967) in Chemistry and MS (1967) in Pharmacology from Philadelphia College of Pharmacy and Science. He received his Ph.D. (1971) in Pharmacology from the University of Pennsylvania and was awarded Doctor Honoris Causa, 2005 from the Medical University of Silesia in Katowice Poland. Following his post-doctoral training in New Orleans he was appointed to the faculty at Louisiana State University. He joined the faculty in the department of Pharmacology at ETSU in 1978, rising to the rank of Professor in 1984. Dr. Kostrzewa is a world recognized authority in the neuropharmacological aspects of Parkinson Disease and ADHD, with a primary focus on Serotoninergic, histaminergic and dopaminergic systems. 

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Table of contents (97 chapters)

  • Survey of Selective Neurotoxins

    Kostrzewa, Richard M.

    Pages 3-67

  • Necroptosis, a Potential Therapeutic Target for Neurological Disorders

    Chen, Jing (et al.)

    Pages 69-93

  • RCSN Cell System for Identifying Dopaminergic Neurotoxicity

    Caviedes, Pablo (et al.)

    Pages 95-108

  • Microglia: Neuroprotective and Neurodestructive Properties

    Harry, G. Jean (et al.)

    Pages 109-132

  • 6-Hydroxydopamine Lesioning of Dopamine Neurons in Neonatal and Adult Rats Induces Age-Dependent Consequences

    Papadeas, Sophia T. (et al.)

    Pages 133-198

Buy this book

eReference $679.00
price for USA (gross)
  • ISBN 978-1-4614-5836-4
  • Free shipping for individuals worldwide
Print $679.00
price for USA
  • ISBN 978-1-4614-5835-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Print + eBook $1,019.00
price for USA
  • ISBN 978-1-4614-7458-6
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
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Bibliographic Information

Bibliographic Information
Book Title
Handbook of Neurotoxicity
Editors
  • Richard Kostrzewa
Copyright
2014
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eReference ISBN
978-1-4614-5836-4
Print ISBN
978-1-4614-5835-7
Print + eBook ISBN
978-1-4614-7458-6
Edition Number
1
Number of Pages
XXXVIII, 2371
Number of Illustrations and Tables
97 b/w illustrations, 147 illustrations in colour
Topics