Immunomics Reviews:

Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines

Editors: Flower, Darren R., Perrie, Yvonne (Eds.)

  • Will address an important emergent area within immunomics: adjuvants
  • Explores ways to make vaccines more effective
  • There is no such book like this one
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eBook $169.00
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  • ISBN 978-1-4614-5070-2
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  • Immediate eBook download after purchase
Hardcover $219.00
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  • ISBN 978-1-4614-5069-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-9795-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology. Conventional approaches to vaccine design and development requires pathogens to be cultivated in the laboratory and the immunogenic molecules within them to be identifiable. Conventional vaccinology is no longer universally successful, particularly for recalcitrant pathogens. By using genomic information we can study vaccine development in silico: 'reverse vaccinology', can identify candidate subunits vaccines by identifying antigenic proteins and by using equally rational approaches to identify novel immune response-enhancing adjuvants.

About the authors

Dr. Darren R Flower. An interdisciplinary scientist, with special interest in bioinformatics, computational chemistry, and cheminformatics, Dr. Flower has wide-ranging experience of the pre-clinical research environment in both academia and the pharmaceutical industry. Before joining Aston University as a Reader, Dr. Flower was a Jenner Research Fellow and Principal Investigator at the University of Oxford; and formerly a Senior Group Leader managing a large research group at The Edward Jenner Institute for Vaccine Research. Before that, Dr. Flower was a drug discovery scientist in the Pharmaceutical industry. Dr. Flower is a Fellow of the Royal Society of Chemistry, and the author of over 150 research papers and reviews, and 7 Books, including the monograph: Bioinformatics for Vaccinology.

Professor Yvonne Perrie is Pharmacist whose research focuses on the development on delivery systems for drugs and vaccines. Prof. Perrie is currently Head of Pharmacy and Chair in Drug Delivery within Aston University.  Prof. Perrie received her Ph.D. from the University of London, UK where she investigated the use of liposomes for gene delivery under the supervision of Professor Gregory Gregoriadis. Prof. Perrie then joined a newly established Drug Delivery Company, Lipoxen Technologies Ltd., prior to taking her post at Aston University. Prof. Perrie is currently Chair of the UK and Ireland Controlled Release Society and has approximately 100 research papers and reviews focusing on the research and development of drug delivery systems.

Table of contents (14 chapters)

  • Immunomic Discovery of Adjuvants, Delivery Systems, and Candidate Subunit Vaccines: A Brief Introduction

    Flower, Darren R. (et al.)

    Pages 1-11

  • Bacterial Genomes and Vaccine Design

    Cafardi, Valeria (et al.)

    Pages 13-37

  • Identification of Candidate Vaccine Antigens In Silico

    Flower, Darren R. (et al.)

    Pages 39-71

  • Post-genomic Antigen Discovery: Bioinformatical Approaches to Reveal Novel T Cell Antigens of Mycobacterium bovis

    Vordermeier, Martin (et al.)

    Pages 73-90

  • Genome-Based Computational Vaccine Discovery by Reverse Vaccinology

    He, Yongqun

    Pages 91-104

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-5070-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-5069-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-9795-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines
Editors
  • Darren R. Flower
  • Yvonne Perrie
Series Title
Immunomics Reviews:
Series Volume
5
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-5070-2
DOI
10.1007/978-1-4614-5070-2
Hardcover ISBN
978-1-4614-5069-6
Softcover ISBN
978-1-4899-9795-1
Edition Number
1
Number of Pages
X, 314
Topics