AAPS Advances in the Pharmaceutical Sciences Series

Microdialysis in Drug Development

Editors: Müller, Markus (Ed.)

  • Authored by international experts
  • Provides a comprehensive overview of microdialysis and its application for measuring drug distribution in drug development
  • Describes cutting edge field
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eBook $159.00
price for USA (gross)
  • ISBN 978-1-4614-4815-0
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  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-1-4614-4814-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
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  • ISBN 978-1-4899-9621-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues. Microdialysis is a key semi-invasive sampling technique to measure in vivo drug penetration to the target site in humans, the method being feasible in virtually every organ. Authored by international experts in this cutting edge field, this book will provide a comprehensive overview of microdialysis and its application for measuring drug distribution in drug development.

About the authors

Prof. Markus Müller, MD is Head of the Department of Clinical Pharmacology at the Medical University of Vienna in Austria. He is specialized in Internal Medicine and Clinical Pharmacology and is an international expert in clinical research. He has published over 80 articles on the use and methodology of microdialysis in clinical drug development.

Table of contents (16 chapters)

  • Introduction to the Microdialysis Technology

    Müller, Markus

    Pages 3-12

  • Recovery and Calibration Techniques: Toward Quantitative Microdialysis

    Lange, Elizabeth C. M.

    Pages 13-33

  • Analytical Considerations for Microdialysis Sampling

    Cooley, Justin C. (et al.)

    Pages 35-66

  • Regulatory Aspects of Microdialysis: A United States Food and Drug Administration Perspective

    Shukla, Chinmay (et al.)

    Pages 67-80

  • Microdialysis in CNS PKPD Research: Unraveling Unbound Concentrations

    Hammarlund-Udenaes, Margareta

    Pages 83-102

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-1-4614-4815-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-1-4614-4814-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • ISBN 978-1-4899-9621-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Microdialysis in Drug Development
Editors
  • Markus Müller
Series Title
AAPS Advances in the Pharmaceutical Sciences Series
Series Volume
4
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
American Association of Pharmaceutical Scientists
eBook ISBN
978-1-4614-4815-0
DOI
10.1007/978-1-4614-4815-0
Hardcover ISBN
978-1-4614-4814-3
Softcover ISBN
978-1-4899-9621-3
Series ISSN
2210-7371
Edition Number
1
Number of Pages
XII, 340
Topics