Cancer Drug Discovery and Development

Advances in DNA Repair in Cancer Therapy

Editors: Panasci, Lawrence, Aloyz, Raquel, Alaoui-Jamali, Moulay (Eds.)

  • Reveals the latest developments in DNA repair in cancer therapy and the latest progress in research
  • Discusses novel DNA repair enzymes such as PARP and DNA-PK
  • Appeals to cancer researchers as well as oncologists
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eBook $189.00
price for USA (gross)
  • ISBN 978-1-4614-4741-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-4614-4740-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4899-9308-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
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About this book

​A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK. The book captures-for both cancer researchers and oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.​

Table of contents (12 chapters)

  • Repair of DNA Interstrand Cross-links Produced by Cancer Chemotherapeutic Drugs

    Wang, Anderson T. (et al.)

    Pages 1-23

  • DNA-PK, a Pharmacological Target in Cancer Chemotherapy and Radiotherapy?

    Salles, Bernard (et al.)

    Pages 25-44

  • Growth Factor Receptor Signaling, DNA Damage Response, and Cancer Cell Susceptibility to Chemotherapy and Relapses

    Alaoui-Jamali, Moulay (et al.)

    Pages 45-74

  • The Relationship Between DNA-Repair Genes, Cellular Radiosensitivity, and the Response of Tumors and Normal Tissues to Radiotherapy

    Murray, David (et al.)

    Pages 75-128

  • Important Roles of ERCC1 in DNA Repair and Targeted Therapy

    Hu, Jennifer J. (et al.)

    Pages 129-142

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4614-4741-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-4614-4740-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4899-9308-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Advances in DNA Repair in Cancer Therapy
Editors
  • Lawrence Panasci
  • Raquel Aloyz
  • Moulay Alaoui-Jamali
Series Title
Cancer Drug Discovery and Development
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-4741-2
DOI
10.1007/978-1-4614-4741-2
Hardcover ISBN
978-1-4614-4740-5
Softcover ISBN
978-1-4899-9308-3
Series ISSN
2196-9906
Edition Number
1
Number of Pages
VIII, 312
Topics