Astrovirus Research

Essential Ideas, Everyday Impacts, Future Directions

Editors: Schultz-Cherry, Stacey (Ed.)

  • First book of its kind
  • Would remain up-to-date for 3-5 years
  • Will be of great interest to professionals and researchers from many different fields, including public health and food safety experts, poultry specialists, microbiologists, virologists, pediatricians, and veterinarians​
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eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-4735-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-4734-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-9406-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Astroviruses were first identified in the feces of children in 1975.  Since then, they have been found in ~ 3 to 20% of children with diarrhea.  Given that serological studies have demonstrated that up to 90% of children have been exposed to at least one strain of astrovirus by age 9, the prevalence of infection may be much higher.  Supporting this are studies demonstrating that astroviruses can also be isolated in a subset of asymptomatic individuals, suggesting that a proportion of infected individuals shed the virus asymptomatically or for some time after the resolution of other symptoms of infection.  Asymptomatic carriers may be a major reservoir for astroviruses in the environment and could contribute to dissemination of the virus.  Astroviruses are extremely stable in the environment and can be transmitted nosocomially, directly from infected individuals and potentially animals, and through contaminated food and water. Although typically an acute disease, astrovirus infection in premature infants may be associated with the development of necrotizing enterocolitis and in new-onset celiac disease in children.  Immunocompromised children are even more susceptible often developing persistent infections that lead to wasting or even systemic infections associated with fatal encephalitis.   In spite of its importance, little is known about astrovirus pathogenesis, molecular biology, epidemiology, or cell biology.  The goal of this book is to provide the latest and most up-to-date information on this medically important and rapidly evolving group of viruses.  It will include sections on the history of astroviruses and their disease in humans; information on viral replication and immune responses; new information on how astroviruses induce disease including the expression of a viral enterotoxin regulating intestinal epithelial cell tight junctions, the isolation and identification of new astrovirus genotypes in mammals including humans, and astroviruses of veterinary importance.  Finally, the book will also introduce the complexity of astrovirus epidemiology and potential as an important new zoonotic disease, and its role in food-borne disease.  This will be the first book of its kind and will be of great interest to microbiologists, virologists, infectious disease specialists, immunologists, pediatricians, public health and food safety experts, veterinarians, poultry industry specialists, and researchers and clinicians interested in enteritis. ​

Table of contents (9 chapters)

  • Epidemiology of Human Astroviruses

    Bosch, Albert (et al.)

    Pages 1-18

  • Replication Cycle of Astroviruses

    Méndez, Ernesto (et al.)

    Pages 19-45

  • Astrovirus Structure and Assembly

    Dubois, Rebecca M. (et al.)

    Pages 47-64

  • Astrovirus Pathogenesis

    Meliopoulos, Victoria (et al.)

    Pages 65-77

  • Immune Responses

    Krishna, Neel K. (et al.)

    Pages 79-95

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-1-4614-4735-1
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4614-4734-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $219.00
price for USA
  • ISBN 978-1-4899-9406-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Astrovirus Research
Book Subtitle
Essential Ideas, Everyday Impacts, Future Directions
Editors
  • Stacey Schultz-Cherry
Copyright
2013
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-4735-1
DOI
10.1007/978-1-4614-4735-1
Hardcover ISBN
978-1-4614-4734-4
Softcover ISBN
978-1-4899-9406-6
Edition Number
1
Number of Pages
XIV, 186
Topics