Mitochondria and Their Role in Cardiovascular Disease

Authors: Marín-García, José

  • Brings readers up-to-date on the many significant advances in the field of mitochondrial cardiovascular medicine
  • Presents cutting-edge information on the expanding role of mitochondria on major cardiovascular diseases
  • Emphasis on biological understanding and clinical impact
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eBook $219.00
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  • ISBN 978-1-4614-4599-9
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  • Immediate eBook download after purchase
Hardcover $279.00
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  • ISBN 978-1-4614-4598-2
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  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
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  • ISBN 978-1-4899-9766-1
  • Free shipping for individuals worldwide
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About this book

Over the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically. We now know that these organelles play a critical role in the normal and in the damaged heart. Written by Dr. José Marín-García, Director of the Molecular Cardiology and Neuromuscular Institute, Mitochondria and Their Role in Cardiovascular Disease brings readers up- to-date on the many significant advances in the field of mitochondrial cardiovascular medicine.  The book begins with a general introduction to mitochondria, followed by laboratory methods to study the structure and function of the organelle, regulation of replication and biogenesis, and the mechanisms and functional consequences of mitophagia and mitochondrial dynamics. Subsequent chapters deal with mitochondrial oxidative stress and the role that the organelle plays in cell signaling and cell death. Discussions will be undertaken on the biochemistry of mitochondrial cell signaling, including the nature of the proteins engaged in these processes, many of them only recently discovered. Later chapters examine the role of mitochondria and mitochondrial abnormalities in cardiovascular diseases, including their diagnosis, therapeutic options currently available, animal models of mitochondrial disease, and new frontiers in mitochondria cardiovascular medicine, including areas of research that are relatively new or developing, such as proteomics, next generation sequencing, and systems biology.


About the authors

José Marín-García, MD

The Molecular Cardiology and Neuromuscular Institute

Highland Park, NJ, USA

Table of contents (24 chapters)

  • Introduction to Mitochondria in the Heart

    Marín-García, José

    Pages 3-11

  • Methods to Study Mitochondrial Structure and Function

    Marín-García, José

    Pages 13-27

  • Mitochondrial Structure, Composition, and Dynamics

    Marín-García, José

    Pages 29-57

  • Mitochondrial Biogenesis

    Marín-García, José

    Pages 59-97

  • Mechanisms of Bioenergy Production in Mitochondria

    Marín-García, José

    Pages 99-121

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-1-4614-4599-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-1-4614-4598-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-1-4899-9766-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Mitochondria and Their Role in Cardiovascular Disease
Authors
Copyright
2013
Publisher
Springer US
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-4599-9
DOI
10.1007/978-1-4614-4599-9
Hardcover ISBN
978-1-4614-4598-2
Softcover ISBN
978-1-4899-9766-1
Edition Number
1
Number of Pages
XX, 500
Topics