SpringerBriefs in Genetics

Hereditary Retinopathies

Progress in Development of Genetic and Molecular Therapies

Authors: Humphries, P., Humphries, M., Tam, L.C.S., Farrar, J.G., Kenna, P.F., Campbell, M., Kiang, A.-S.

  • Provides a snap-shot of current gene and drug-based therapies for hereditary retinal disorders
  • The authors explore emerging topics such as novel gene or drug delivery methods to the retina and retinal diseases caused by protein misfolding and aggregation
  • Describes current developments and future prospects for the application of gene therapy
see more benefits

Buy this book

eBook $34.99
price for USA (gross)
  • ISBN 978-1-4614-4499-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $49.95
price for USA
  • ISBN 978-1-4614-4498-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The hereditary retinopathy, retinitis pigmentosa (RP), which affects 1 in 3,500 people worldwide, is the most common cause of registered visual handicap among those of the working age in developed countries. RP is a highly variable disorder where patients may develop symptomatic visual loss in early childhood, while others may remain asymptomatic until mid-adulthood. Most cases of RP segregate in autosomal dominant, recessive or X-linked recessive modes, with approximately 41 genes being implicated in disease pathology to date (RetNet). The extensive genetic heterogeneity associated with autosomal dominant RP (adRP) is an undisputed hindrance to the development of genetically based therapeutics.

Table of contents (3 chapters)

  • Introduction

    Humphries, Pete (et al.)

    Pages 1-10

  • Gene-Based Medicines Targeting Genetic Defects Directly and Molecular Pathologies Common to Multiple Forms of Disease

    Humphries, Pete (et al.)

    Pages 11-30

  • Molecular Medicines

    Humphries, Pete (et al.)

    Pages 31-46

Buy this book

eBook $34.99
price for USA (gross)
  • ISBN 978-1-4614-4499-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $49.95
price for USA
  • ISBN 978-1-4614-4498-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Hereditary Retinopathies
Book Subtitle
Progress in Development of Genetic and Molecular Therapies
Authors
Series Title
SpringerBriefs in Genetics
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
The Author(s)
eBook ISBN
978-1-4614-4499-2
DOI
10.1007/978-1-4614-4499-2
Softcover ISBN
978-1-4614-4498-5
Series ISSN
2191-5563
Edition Number
1
Number of Pages
VII, 46
Number of Illustrations and Tables
3 b/w illustrations, 5 illustrations in colour
Topics