SpringerBriefs in Neuroscience

Serotonin and Anxiety

Neuroanatomical, Pharmacological, and Functional Aspects

Authors: Maximino, Caio

  • A unique, integrated approach to the organization of brain structures that play a part in defensive behavior
  • Focuses on animal research
  • Presents interpretations of behavioral, pharmacological, neuroanatomical, and electrophysiological findings​
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eBook $34.99
price for USA (gross)
  • ISBN 978-1-4614-4048-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $49.95
price for USA
  • ISBN 978-1-4614-4047-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Anxiety disorders have long been a research subject for scientists in different areas of inquiry, and the particular role of serotonin – the neurotransmitter which has probably most captured the imagination of laymen and academics alike – is as elusive as the clinical aspects of serotonergic medications. Why are drugs acting at certain serotonin receptors efficacious against generalized anxiety disorder, but not panic disorder? Why is the inverse true for monoamine oxidase inhibitors? These clinically relevant issues are clarified by the neurochemical, anatomical and physiological organization of the serotonergic system.

In this book, the author summarizes the latest findings regarding the role of serotonin in modulating the activity of brain regions which organize behavioral patterns associated with fear, anxiety and stress. The emergent picture is one of far greater complexity than previously thought: while the serotonergic innervation of those brain regions arises from the same structure – the dorsal raphe nucleus – that structure is not homogeneous from anatomical, physiological and neurochemical points of view, nor are its projections to the cerebral aversive and behavioral inhibition systems.

The diverse findings which compose this picture of complexity – whether they arise from developmental neurobiology, electrophysiology, neurochemistry, neuroendocrinology, neuropsychopharmacology or behavioral neuroscience – are integrated in this book. Advanced undergraduate, graduate students, and researchers will benefit from the information. The result sheds light on many important questions regarding the neuroanatomical, pharmacological and functional aspects of the role of serotonin in anxiety disorders, and points to future avenues of research.

Reviews

From the reviews:

“This is a concise, information-packed, to-the-point book on the neurobiology of serotonin in anxiety. … Researchers studying anxiety and the role of serotonin might find this useful. … Each chapter is referenced with relevant and timely citations from the scientific literature.” (Michael Joel Schrift, Doody’s Review Service, November, 2012)

Table of contents (6 chapters)

  • Introduction

    Maximino, Caio

    Pages 1-14

  • Serotonin in the Nervous System of Vertebrates

    Maximino, Caio

    Pages 15-36

  • Nodal Structures in Anxiety-Like and Panic-Like Responses

    Maximino, Caio

    Pages 37-78

  • The Deakin–Graeff Hypothesis

    Maximino, Caio

    Pages 79-85

  • Topographic Organization of DRN

    Maximino, Caio

    Pages 87-103

Buy this book

eBook $34.99
price for USA (gross)
  • ISBN 978-1-4614-4048-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $49.95
price for USA
  • ISBN 978-1-4614-4047-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Serotonin and Anxiety
Book Subtitle
Neuroanatomical, Pharmacological, and Functional Aspects
Authors
Series Title
SpringerBriefs in Neuroscience
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
The Author(S)
eBook ISBN
978-1-4614-4048-2
DOI
10.1007/978-1-4614-4048-2
Softcover ISBN
978-1-4614-4047-5
Series ISSN
2191-558X
Edition Number
1
Number of Pages
X, 111
Number of Illustrations and Tables
2 b/w illustrations, 5 illustrations in colour
Topics