LC-MS in Drug Bioanalysis

Editors: Xu, Q. Alan, Madden, Timothy L. (Eds.)

  • First book to discuss the development and validation of LC-MS methods and their applications in analyzing a wide range of drugs
  • Will facilitate pharmacologists, toxicologists, and physicians finding relevant analytical techniques in their clinical research
  • No other title in the subject area deals with so many methodological chapters
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eBook $139.00
price for USA (gross)
  • ISBN 978-1-4614-3828-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-4614-3827-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-4899-9089-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Clinical pharmacology plays an important role in today’s medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography – mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.

Table of contents (14 chapters)

  • Internal Standards for Quantitative LC-MS Bioanalysis

    Tan, Aimin (et al.)

    Pages 1-32

  • Method Development, Validation, and Sample Analysis for Regulated Quantitative Bioanalysis Using LC-MS/MS

    Meng, Min (et al.)

    Pages 33-66

  • Impact of Sampling Paper/Cards on Bioanalytical Quantitation via Dried Blood Spots by Liquid Chromatography-Mass Spectrometry

    Zhang, Jun (et al.)

    Pages 67-80

  • Highly Sensitive Pharmaceutical and Clinical Analysis Using Selective Solid-Phase Extraction Coupled to Microflow Liquid Chromatography and Isotope-Dilution Mass Spectrometry

    Yu, Haoying (et al.)

    Pages 81-107

  • Pitfalls of LC-MS/MS in the Clinical Laboratory

    Seger, Christoph (et al.)

    Pages 109-126

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-1-4614-3828-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-4614-3827-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • ISBN 978-1-4899-9089-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
LC-MS in Drug Bioanalysis
Editors
  • Q. Alan Xu
  • Timothy L. Madden
Copyright
2012
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-3828-1
DOI
10.1007/978-1-4614-3828-1
Hardcover ISBN
978-1-4614-3827-4
Softcover ISBN
978-1-4899-9089-1
Edition Number
1
Number of Pages
XII, 472
Topics