Methods in Molecular Biology

Intrinsically Disordered Protein Analysis

Volume 2, Methods and Experimental Tools

Editors: Uversky, Vladimir N., Dunker, A. Keith (Eds.)

  • Details experimental methods used to identify IDP's and to analyze their structure
  • Provides step-by-step detail essential fro reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $129.00
price for USA (gross)
  • ISBN 978-1-4614-3704-8
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  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-4614-3703-1
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About this book

Over the past decade, there has been an explosive development of research of intrinsically disordered proteins (IDPs), which are also known as unfolded proteins. Structural biologists now recognize that the functional diversity provided by disordered regions complements the functional repertoire of ordered protein regions. In Intrinsically Disordered Protein Analysis: Methods and Experimental Tools, expert researchers explore the high abundance of IDPs in various organisms, their unique structural features, numerous functions, and crucial associations with different diseases. Volume 2 includes sections on single molecule techniques, methods to assess protein size and shape, analyzing conformational behavior, mass-spectrometry, expression and purification of IDP’s. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.

Thorough and intuitive, Intrinsically Disordered Protein Analysis: Methods and Experimental Tools helps scientists further their investigations of these fascinating and dynamic molecules.

Table of contents (30 chapters)

  • Immobilization of Proteins for Single-Molecule Fluorescence Resonance Energy Transfer Measurements of Conformation and Dynamics

    Choi, Ucheor B. (et al.)

    Pages 3-20

  • Application of Confocal Single-Molecule FRET to Intrinsically Disordered Proteins

    Schuler, Benjamin (et al.)

    Pages 21-45

  • Single-Molecule Force Spectroscopy of Chimeric Polyprotein Constructs Containing Intrinsically Disordered Domains

    Brucale, Marco (et al.)

    Pages 47-56

  • Visualization of Mobility by Atomic Force Microscopy

    Ando, Toshio (et al.)

    Pages 57-69

  • Unequivocal Single-Molecule Force Spectroscopy of Intrinsically Disordered Proteins

    Oroz, Javier (et al.)

    Pages 71-87

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-4614-3704-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-4614-3703-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Intrinsically Disordered Protein Analysis
Book Subtitle
Volume 2, Methods and Experimental Tools
Editors
  • Vladimir N. Uversky
  • A. Keith Dunker
Series Title
Methods in Molecular Biology
Series Volume
896
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-4614-3704-8
DOI
10.1007/978-1-4614-3704-8
Hardcover ISBN
978-1-4614-3703-1
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 454
Topics