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Energy Balance and Hematologic Malignancies

  • Book
  • © 2012

Overview

Editors:
  1. Steven D. Mittelman

    1. Keck School of Medicine, Los Angeles, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Nathan A. Berger

    1. School of Medicine, Center for Science, Health & Society, Case Western Reserve University, Cleveland, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Focuses on the relation of obesity to hematologic malignancies, the epidemiology, potential mechanisms, and therapeutic considerations on energy balance
  • Adds to the burgeoning field of information on metabolism and cancer
  • Includes effects on pharmacologic and physical approaches as well as the delayed effects of therapy on energy balance

Part of the book series: Energy Balance and Cancer (EBAC, volume 5)

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-x
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  2. The Epidemiology of Obesity and Hematologic Malignancies

    • Lauren R. Teras, Alpa V. Patel
    Pages 1-30

  3. Adipocytes, Lipid Metabolism, and Hematopoiesis

    • Jeffrey M. Gimble
    Pages 31-45

  4. Mechanisms Linking Obesity and Leukemia Prognosis

    • Steven D. Mittelman, Anna Butturini
    Pages 47-69

  5. Obesity and Multiple Myeloma

    • Tracey Beason, Graham Colditz
    Pages 71-95

  6. The Impact of Obesity on Pharmacokinetics and Dosing of Leukemia Chemotherapy

    • Jennifer Kendrick, Dawn Warkentin, Mary H. H. Ensom
    Pages 97-127

  7. The Impact of Obesity on Stem Cell Transplant

    • Willis H. Navarro, Fausto R. Loberiza Jr.
    Pages 129-140

  8. Obesity Following Childhood Cancer: Mechanisms and Consequences

    • Emily S. Tonorezos, Kevin C. Oeffinger
    Pages 141-158

  9. Physical Activity and Recovery from Hematological Malignancy

    • Luisa Soares-Miranda, Carmen Fiuza-Luces, Alejandro Lucia
    Pages 159-175

  10. Back Matter

    Pages 177-184
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Keywords

About this book

The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from childhood to the elderly and include leukemia, myeloma, lymphoma and others. In addition to the etiologic association between obesity and hematologic malignancies, the presence of obesity has profound effects on therapy by impacting pharmacokinetics of chemotherapeutic agents, dose, adipocyte metabolism and drug distribution. These may be particularly important in hematopoietic stem cell transplantation. Another important aspect of the association of obesity with hematologic malignancies is the increased incidence of obesity in children who successfully complete therapy for acute lymphoblastic leukemia. This and other observations indicate important relations between the hematopoietic systems and fat metabolism. This volume on Energy Balance in Hematologic Malignancies will provide an important volume in this series and a basis for better understanding etiology, mechanisms, therapeutics implications and experimental approaches. This volume of energy balance and cancer will focus on the relation of obesity to hematologic malignancies, the epidemiology, potential mechanisms, and thereapeutic considerations including effects on pharmacologic and physical approaches as well as the delayed effects of therapy on energy balance.

Reviews

From the reviews:

“This book addresses a serious public health issue -- obesity and how it affects the incidence, treatment, and outcomes in patients with hematologic malignancies. … It targets researchers in the obesity-cancer field, clinicians, pharmacists, and ancillary caregivers. … a good resource for select patient populations. … The book has enough diagrams and tables to give a visual depiction of what the text is explaining. … I am not aware of any other book that addresses the issue of obesity and hematological malignancies in this detail.” (Kehinde Adekola, Doody’s Review Service, July, 2012)

Editors and Affiliations

  • Keck School of Medicine, Los Angeles, USA

    Steven D. Mittelman

  • School of Medicine, Center for Science, Health & Society, Case Western Reserve University, Cleveland, USA

    Nathan A. Berger

Bibliographic Information

  • Book Title: Energy Balance and Hematologic Malignancies

  • Editors: Steven D. Mittelman, Nathan A. Berger

  • Series Title: Energy Balance and Cancer

  • DOI: https://doi.org/10.1007/978-1-4614-2403-1

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media LLC 2012

  • Hardcover ISBN: 978-1-4614-2402-4Published: 28 February 2012

  • Softcover ISBN: 978-1-4899-9421-9Published: 13 April 2014

  • eBook ISBN: 978-1-4614-2403-1Published: 25 February 2012

  • Series ISSN: 2199-2622

  • Series E-ISSN: 2199-2630

  • Edition Number: 1

  • Number of Pages: X, 186

  • Topics: Pharmacology/Toxicology, Cancer Research

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