Biological and Medical Physics, Biomedical Engineering

Computational Modeling of Biological Systems

From Molecules to Pathways

Editors: Dokholyan, Nikolay V (Ed.)

  • Reviews established modeling approaches of biological systems across multiple length and time scales from molecules to cells
  • Covers recent and emerging computational techniques in modelling biological systems
  • Provides a fresh outlook on the topic by covering multiscale modelling and includes a section on molecular evolution
  • Can be used as a guide for selecting methods for studying biological systems
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eBook $109.00
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  • ISBN 978-1-4614-2146-7
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Hardcover $149.00
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  • ISBN 978-1-4614-2145-0
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  • ISBN 978-1-4899-8750-1
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About this book

Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant systems.

About the authors

Dr. Nikolay Dokholyan joined the Department of Biochemistry and Biophysics in the University of North Carolina at Chapel Hill, School of Medicine as an Assistant Professor. In 2008, Dr. Dokholyan was promoted as Associate Professor. Dr. Dokholyan is currently the Director of the Center for Computational and Systems Biology and the Graduate Director of the Program in Molecular and Cellular Biophysics at UNC.

Table of contents (15 chapters)

  • Introduction to Molecular Dynamics: Theory and Applications in Biomolecular Modeling

    Wang, Yi (et al.)

    Pages 3-30

  • The Many Faces of Structure-Based Potentials: From Protein Folding Landscapes to Structural Characterization of Complex Biomolecules

    Noel, Jeffrey K. (et al.)

    Pages 31-54

  • Discrete Molecular Dynamics Simulation of Biomolecules

    Ding, Feng (et al.)

    Pages 55-73

  • Small Molecule Docking from Theoretical Structural Models

    Novoa, Eva Maria (et al.)

    Pages 75-95

  • Homology Modeling: Generating Structural Models to Understand Protein Function and Mechanism

    Ramachandran, Srinivas (et al.)

    Pages 97-116

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-4614-2146-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.00
price for USA
  • ISBN 978-1-4614-2145-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $149.00
price for USA
  • ISBN 978-1-4899-8750-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Computational Modeling of Biological Systems
Book Subtitle
From Molecules to Pathways
Editors
  • Nikolay V Dokholyan
Series Title
Biological and Medical Physics, Biomedical Engineering
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-2146-7
DOI
10.1007/978-1-4614-2146-7
Hardcover ISBN
978-1-4614-2145-0
Softcover ISBN
978-1-4899-8750-1
Series ISSN
1618-7210
Edition Number
1
Number of Pages
VI, 366
Topics