Advances in Neurobiology

Neural Metabolism In Vivo

Editors: Choi, In-Young, Gruetter, Rolf (Eds.)

  • Uses full-color figures to illustrate difficult concepts
  • Provides a comprehensive overview of neurobiology
  • Includes cutting-edge research
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eBook $229.00
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  • ISBN 978-1-4614-1788-0
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  • Immediate eBook download after purchase
Hardcover $289.00
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  • ISBN 978-1-4614-1787-3
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About this book

From the preface:

 “Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain.  Investigation of neural activity of the living brain via neurovascular coupling using multimodal imaging techniques extended our understanding of fundamental neurophysiological mechanisms, regulation of cerebral blood flow in connection to neural activity and the interplay between neurons, astrocytes and blood vessels.  Constant delivery of glucose and oxygen for energy metabolism is vital for brain function, and the physiological basis of neural activity can be assessed through measurements of cerebral blood flow and consumption of glucose and oxygen….

 This book presents the complex physiological and neurochemical processes of neural metabolism and function in response to various physiological conditions and pharmacological stimulations.  Neurochemical detection technologies and quantitative aspects of monitoring cerebral energy substrates and other metabolites in the living brain are described under the “Cerebral metabolism of antioxidants, osmolytes and others in vivo” section.  Altogether, the advent of new in vivo tools has transformed neuroscience and neurobiology research, and demands interdisciplinary approaches as each technology could only approximate a very small fraction of the true complexity of the underlying biological processes.  However, translational values of the emerging in vivo methods to the application of preclinical to clinical studies cannot be emphasized enough.  Thus, it is our hope that advances in our understanding of biochemical, molecular, functional and physiological processes of the brain could eventually help people with neurological problems, which are still dominated by the unknowns.”

 -- In-Young Choi and Rolf Gruetter

Reviews

“This is a good textbook concerning the NMR, rms, and brain metabolites. … I recommend this book for biochemists, neurologists, and physiologists with interests in the brain metabolic disorders of acetate, glutamate, aspartate, GABA, creatine, creatine kinases, and other isoenzymes. … This is a good book also for imagers and others interested in brain pathology correlation.” (Joseph J. Grenier, Amazon.com, May, 2015)


Table of contents (41 chapters)

  • Introduction to Nuclear Magnetic Resonance (NMR) Methods

    Song, Allen W.

    Pages 3-31

  • Hardware Requirements for In Vivo Nuclear Magnetic Resonance Studies of Neural Metabolism

    Merkle, Hellmut (et al.)

    Pages 33-64

  • Diffusion Sensitive Magnetic Resonance Imaging of the Central Nervous System

    Neil, Jeffrey J. (et al.)

    Pages 65-78

  • Tools to Enhance the Contrast in MR Images: From Lanthanide Complexes and Iron Oxide Particles to MEMRI

    Linden, Annemie (et al.)

    Pages 79-132

  • Principles of 1H NMR Spectroscopy In Vivo

    Graaf, Robin A.

    Pages 133-147

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4614-1788-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4614-1787-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Neural Metabolism In Vivo
Editors
  • In-Young Choi
  • Rolf Gruetter
Series Title
Advances in Neurobiology
Series Volume
4
Copyright
2012
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-1788-0
DOI
10.1007/978-1-4614-1788-0
Hardcover ISBN
978-1-4614-1787-3
Series ISSN
2190-5215
Edition Number
1
Number of Pages
XXI, 1169
Topics