Advances in Experimental Medicine and Biology

Viral Molecular Machines

Editors: Rossmann, Michael G., Rao, Venigalla B. (Eds.)

  • Written by leaders in their respective fields
  • Uses the best examples from bacteriophages and animal viruses, many causing infectious diseases of public health importance
  • Conveys state of the art knowledge of the topic generated by combining X-ray crystallography, high resolution electron microscopy, molecular genetics, biochemistry, and single molecule biophysics
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eBook $259.00
price for USA (gross)
  • ISBN 978-1-4614-0980-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $329.00
price for USA
  • ISBN 978-1-4614-0979-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural components, genome packaging and maturation into an infectious virion.

Each chapter will describe the components of the respective machine in molecular or atomic detail, genetic and biochemical analyses, and mechanism. Topics are carefully selected so that the reader is exposed to systems where there is a substantial infusion of new knowledge in recent years, which greatly elevated the fundamental mechanistic understanding of the respective molecular machine. The authors will be encouraged to simplify the detailed knowledge to basic concepts, include provocative new ideas, as well as design colorful graphics, thus making the cutting-edge information accessible to broad audience.

Table of contents (28 chapters)

  • Viruses: Sophisticated Biological Machines

    Rossmann, Michael G. (et al.)

    Pages 1-3

  • F1-ATPase: A Prototypical Rotary Molecular Motor

    Kinosita, Kazuhiko

    Pages 5-16

  • Principles of Virus Structural Organization

    Prasad, B. V. Venkataram (et al.)

    Pages 17-47

  • Reconstructing Virus Structures from Nanometer to Near-Atomic Resolutions with Cryo-Electron Microscopy and Tomography

    Chang, Juan (et al.)

    Pages 49-90

  • Contractile Tail Machines of Bacteriophages

    Leiman, Petr G. (et al.)

    Pages 93-114

Buy this book

eBook $259.00
price for USA (gross)
  • ISBN 978-1-4614-0980-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $329.00
price for USA
  • ISBN 978-1-4614-0979-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Viral Molecular Machines
Editors
  • Michael G. Rossmann
  • Venigalla B. Rao
Series Title
Advances in Experimental Medicine and Biology
Series Volume
726
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-0980-9
DOI
10.1007/978-1-4614-0980-9
Hardcover ISBN
978-1-4614-0979-3
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIV, 687
Topics