Advances in Experimental Medicine and Biology

Notch Signaling in Embryology and Cancer

Editors: Reichrath, Jörg, Reichrath, Sandra (Eds.)

  • Comprehensive in scope, covers an overview on our present knowledge of the role of Notch signalling for embryology and cancer, with a focus on new findings in molecular biology
  • Topics are discussed in-depth by leading researchers and clinicians range from the newest findings in cellular and molecular pathology to new concepts for prophylaxis and treatment of cancer
  • Brings the diverse scientific and clinical fields together in one definitive and up-to-date volume
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Hardcover $289.00
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About this book

The goal of this volume is to comprehensively cover a highly readable overview on our present knowledge of the role of Notch signalling for embryology and cancer, with a focus on new findings in molecular biology. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in cellular and molecular pathology to new concepts for prophylaxis and treatment of cancer. Experts in the field as well as scientists and health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of this book to summarize essential up-to-date information for every clinician or scientist interested in the role of Notch signalling in embryology and cancer. We hope that this volume will be adopted as the standard text in this area of science and will stimulate new interest in the role of Notch signalling for embryology and cancer. We further hope that this compendium will serve as both a source for current researchers and a guide to stimulate and assist those in related disciplines to enter this exciting field of research.

About the authors

JÖRG REICHRATH is Professor for Dermatology and Deputy Director of the Clinic for Dermatology, Allergology and Venerology at the Saarland University Hospital in Homburg/Saar, Germany. Main research interests include photobiology, dermato-endocrinology and dermato-oncology. He is a member of numerous national and international scientific organizations, including the German Dermatological Society (DDG), the Deutsche Krebsgesellschaft (DKG), the German Dermatologic Cooperative Oncology Group (DeCOG), and the European Society of Dermatological Research (ESDR). He has been awarded numerous prices including the Arnold-Rikli-price 2006. Jörg Reichrath received his academic degrees (Dr. med., venia legendi) from the Saarland University, Germany.

SANDRA REICHRATH is working as a scientist at the Clinic for Internal Medicine of the Saarland University Hospital in Homburg/Saar, Germany. Main research interests include Notch signalling in glioblastoma and skin tumors. She received her academic degrees from the Faculty of Biology of the Albert-Ludwig-University, Freiburg, Germany.

Table of contents (23 chapters)

  • The Molecular Basis of Notch Signaling: A Brief Overview

    Kwon, Sang-Mo (et al.)

    Pages 1-14

  • The Role of Adams in Notch Signaling

    Groot, Arjan J. (et al.)

    Pages 15-36

  • Metabolism and Transportation Pathways Of GDP-Fucose that are Required for the O-Fucosylation Of Notch

    Yamakawa, Tomoko (et al.)

    Pages 37-46

  • Notch Signaling and the Generation of Cell Diversity in Drosophila Neuroblast Lineages

    Udolph, Gerald

    Pages 47-60

  • NEPRO: A Novel Notch Effector for Maintenance of Neural Progenitor Cells in the Neocortex

    Saito, Tetsuichiro

    Pages 61-70

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4614-0899-4
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4614-0898-7
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
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Bibliographic Information

Bibliographic Information
Book Title
Notch Signaling in Embryology and Cancer
Editors
  • Jörg Reichrath
  • Sandra Reichrath
Series Title
Advances in Experimental Medicine and Biology
Series Volume
727
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
Landes Bioscience and Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-0899-4
DOI
10.1007/978-1-4614-0899-4
Hardcover ISBN
978-1-4614-0898-7
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XXII, 322
Number of Illustrations and Tables
61 b/w illustrations, 8 illustrations in colour
Topics