Protein Reviews

The Nucleolus

Editors: Olson, Mark O. J. (Ed.)

  • Covers recent discoveries on novel functions of the nucleolus.
  • Emphasizes nucleolar proteins while also including the crucial importance of nucleic acids.
  • Includes chapters on nucleolar ultrastructure, the locations and dynamics of nucleolar components, and on regulatory systems.
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eBook $229.00
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  • ISBN 978-1-4614-0514-6
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Hardcover $289.00
price for USA
  • ISBN 978-1-4614-0513-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4614-3012-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest.  These new discoveries include not only the novel functions of the nucleouls, but also numerous breakthroughs on its conventional role.  Consequently, a large part of this volume is devoted to traditional functions of the nucleolus.  Recent research has led to so much information that the subject cannot be fully contained within one volume, so this book has focused on recent progress in specialized topics within the general subject.

<i>The Nucleolus</i> is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.  Proteomics has shown that there are hundreds of proteins of unknown function in the nucleolus, which are likely to keep researchers busy for years.  In addition, the roles of many viral components in the nucleolus will continue to intrigue us, hopefully moving beyond the phenomenology that is now the case with many viral components in the nucleolus.  Even now, there is already evidence that we can take advantage of our knowledge of the nucleolus to develop therapeutic strategies, and this book hopes to help build the path to a new era of nucleolar translational medical research.

Table of contents (7 chapters)

  • Crosstalk Between Ribosome Synthesis and Cell Cycle Progression and Its Potential Implications in Human Diseases

    Marie Gérus, Michèle Caizergues-Ferrer, Yves Henry, et al.

    Pages 157-184

  • The Multiple Properties and Functions of Nucleolin

    Rong Cong, Sadhan Das, Philippe Bouvet

    Pages 185-212

  • The Multifunctional Nucleolar Protein Nucleophosmin/NPM/B23 and the Nucleoplasmin Family of Proteins

    Shea Ping Yip, Parco M. Siu, Polly H. M. Leung, et al.

    Pages 213-252

  • Structure and Function of Nopp140 and Treacle

    Fang He, Patrick DiMario

    Pages 253-278

  • New Frontiers in Nucleolar Research: Nucleostemin and Related Proteins

    Robert Y. L. Tsai

    Pages 301-320

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4614-0514-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4614-0513-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4614-3012-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Nucleolus
Editors
  • Mark O. J. Olson
Series Title
Protein Reviews
Series Volume
15
Copyright
2011
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-0514-6
DOI
10.1007/978-1-4614-0514-6
Hardcover ISBN
978-1-4614-0513-9
Softcover ISBN
978-1-4614-3012-4
Edition Number
1
Number of Pages
XXVI, 414
Topics