Applied Bioinformatics and Biostatistics in Cancer Research

Designs for Clinical Trials

Perspectives on Current Issues

Editors: Harrington, David (Ed.)

  • Each chapter will be written by an expert conducting research in the topic of that chapter.
  • This book examines current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, and the design of studies in which missing data is anticipated.
  • The chapters serve as a guidance for statisticians designing trials.
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Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-1-4614-0140-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-1-4614-0139-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4614-2953-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated.  Each chapter will be written by an expert conducting research in the topic of that chapter.  As a collection, the chapters would be intended to serve as a guidance for statisticians designing trials.

Reviews

From the reviews:

“‘Designs for Clinical Trials: Perspectives on Current Issues’ fills the gap between professional journals and school textbooks by addressing a few important, rapidly evolving statistical topics. The book is intended for statistical practitioners like clinical trialists who actively use statistics but do not follow the literature on recent biostatistical thinking.” (Norman M. Goldfarb, Journal of Clinical Research Best Practices, Vol. 9 (2), February, 2013)

Table of contents (8 chapters)

  • Designs for Phase I Trials

    Cheung, Ying Kuen

    Pages 1-27

  • Randomized and Balancing Allocation Schemes for Clinical Trials: Computational Perspectives on Design and Deployment

    Carey, Vincent J. (et al.)

    Pages 29-55

  • Sequential Designs for Clinical Trials

    Kim, KyungMann

    Pages 57-79

  • Sample Size Reestimation for Confirmatory Clinical Trials

    Mehta, Cyrus R.

    Pages 81-108

  • On Stopping a Randomized Clinical Trial for Futility

    Herson, Jay (et al.)

    Pages 109-137

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-1-4614-0140-7
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-1-4614-0139-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-1-4614-2953-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Designs for Clinical Trials
Book Subtitle
Perspectives on Current Issues
Editors
  • David Harrington
Series Title
Applied Bioinformatics and Biostatistics in Cancer Research
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-0140-7
DOI
10.1007/978-1-4614-0140-7
Hardcover ISBN
978-1-4614-0139-1
Softcover ISBN
978-1-4614-2953-1
Series ISSN
2363-9644
Edition Number
1
Number of Pages
XIV, 206
Topics