Epilepsy

Animal and Human Correlations

Authors: McCandless, David W.

  • This volume examines features of animal and human studies related to both simple and complex partial seizures.
  • Typical as well as atypical seizures are described whenever possible, studies in primates receive careful attention.
  • Rather than offering an inclusive survey of every published study relating to epilepsy in animals and humans, the book offers judiciously selected material with clear correlative relevance.
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eBook $219.00
price for USA (gross)
  • ISBN 978-1-4614-0361-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-1-4614-0108-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-1-4899-9747-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7‐9 years, and the “success” rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted in advance by animal studies. Both the time between animal and human attempts plus the success rate need improvement.

About the authors

About the Author:
The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA.

Reviews

“This is a comprehensive text and atlas on animal and human studies of Epilepsy. … I highly recommend this book to the following audiences: students, fellows, researchers, neurologists, neurosurgeons, and undergraduates.” (Joseph J. Grenier, Amazon.com, September, 2015)

“For the clinical neurologists and epileptologists dedicated to the care of children and adults affected with epilepsy, a concise book like Epilepsy … is a good attempt to become a source for those seeking rapid immersion in the essentials of translational epilepsy research that have tried to explain those critical aspects of epileptogenesis that involve acquired and developmental seizures. … it is a good foundation for those looking for a quick initial reference, which may not be available in rapidly accessible vast internet sources.” (Luis E. Bello-Espinosa, The Canadian Journal of Neurological Sciences, Vol. 40 (1), January, 2013)


Table of contents (40 chapters)

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-1-4614-0361-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-1-4614-0108-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-1-4899-9747-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Epilepsy
Book Subtitle
Animal and Human Correlations
Authors
Copyright
2012
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4614-0361-6
DOI
10.1007/978-1-4614-0361-6
Hardcover ISBN
978-1-4614-0108-7
Softcover ISBN
978-1-4899-9747-0
Edition Number
1
Number of Pages
XV, 532
Topics