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DNA Methylation

Biochemistry and Biological Significance

  • Book
  • © 1984

Overview

Editors:
  1. Aharon Razin

    1. Department of Cellular Biology, The Hebrew University Hadassah Medical School, Jerusalem, Israel

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    You can also search for this editor in PubMed   Google Scholar

  2. Howard Cedar

    1. Department of Cellular Biochemistry, The Hebrew University Hadassah Medical School, Jerusalem, Israel

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    You can also search for this editor in PubMed   Google Scholar

  3. Arthur D. Riggs

    1. Beckman Research Institute of the City of Hope, Duarte, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Springer Series in Molecular and Cell Biology (SSMOL)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Introduction and General Overview

    • Aharon Razin, Howard Cedar, Arthur D. Riggs
    Pages 1-10

  3. Type I and Type III Restriction-Modification Enzymes

    • Robert Yuan, Daniel L. Hamilton
    Pages 11-37

  4. Methylases of the Type II Restriction-Modification Systems

    • Hamilton O. Smith, Samuel V. Kelly
    Pages 39-71

  5. The Restriction and Modification DNA Methylases: An Overview

    • Robert Yuan, Hamilton O. Smith
    Pages 73-80

  6. Methylation of Prokaryotic DNA

    • M. G. Marinus
    Pages 81-109

  7. DNA Methylation: DNA Replication and Repair

    • Robert H. Grafstrom, Daniel L. Hamilton, Robert Yuan
    Pages 111-126

  8. DNA Methylation Patterns: Formation and Biological Functions

    • Aharon Razin
    Pages 127-146

  9. DNA Methylation and Gene Expression

    • Howard Cedar
    Pages 147-164

  10. Gene Activation by 5-Azacytidine

    • Peter A. Jones
    Pages 165-187

  11. DNA Methylation in Early Mammalian Development

    • Detlev Jähner, Rudolf Jaenisch
    Pages 189-219

  12. Specific Promoter Methylations Cause Gene Inactivation

    • Walter Doerfler, Klaus-Dieter Langner, Inge Kruczek, Lily Vardimon, Doris Renz
    Pages 221-247

  13. DNA Methylation and Developmental Regulation of Eukaryotic Globin Gene Transcription

    • Che-Kun James Shen
    Pages 249-268

  14. X Inactivation, DNA Methylation, and Differentiation Revisited

    • Arthur D. Riggs
    Pages 269-278

  15. Left-handed Z-DNA and Methylation of d(CpG) Sequences

    • Alexander Rich
    Pages 279-292

  16. Chromatin Structure and Gene Expression

    • Kathleen F. Conklin, Mark Groudine
    Pages 293-351

  17. Gene Methylation Patterns and Expression

    • Joel Yisraeli, Moshe Szyf
    Pages 353-378

  18. Back Matter

    Pages 379-392
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Keywords

About this book

During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known of the chemical constitution of biological systems, the manner in which information was trans­ mitted from one organism to another, or the extent to which the chemical basis of life is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects of life at the molecular level. These great advances have brought with them some breath-taking insights into the molecular mechanisms used by nature for rep­ licating, distributing and modifying biological information. We have learned a great deal about the chemical and physical nature of the macromolecular nucleic acids and proteins, and the manner in which carbohydrates, lipids and smaller molecules work together to provide the molecular setting of living sys­ tems. It might be said that these few decades have replaced a near vacuum of information with a very large surplus. It is in the context of this flood of information that this series of monographs on molecular biology has been organized. The idea is to bring together in one place, between the covers of one book, a concise assessment of the state of the subject in a well-defined field. This will enable the reader to get a sense of historical perspective-what is known about the field today-and a description of the frontiers of research where our knowledge is increasing steadily.

Editors and Affiliations

  • Department of Cellular Biology, The Hebrew University Hadassah Medical School, Jerusalem, Israel

    Aharon Razin

  • Department of Cellular Biochemistry, The Hebrew University Hadassah Medical School, Jerusalem, Israel

    Howard Cedar

  • Beckman Research Institute of the City of Hope, Duarte, USA

    Arthur D. Riggs

Bibliographic Information

  • Book Title: DNA Methylation

  • Book Subtitle: Biochemistry and Biological Significance

  • Editors: Aharon Razin, Howard Cedar, Arthur D. Riggs

  • Series Title: Springer Series in Molecular and Cell Biology

  • DOI: https://doi.org/10.1007/978-1-4613-8519-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag New York Inc. 1984

  • Softcover ISBN: 978-1-4613-8521-9Published: 08 November 2011

  • eBook ISBN: 978-1-4613-8519-6Published: 06 December 2012

  • Series ISSN: 0942-6523

  • Edition Number: 1

  • Number of Pages: 392

  • Topics: Biochemistry, general, Cell Biology

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