Serono Symposia USA

Polycystic Ovary Syndrome

Editors: Chang, R. Jeffrey (Ed.)

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About this book

The term polycystic ovary syndrome (peOS) is meant to describe a clinical endocrinopathy characterized by menstrual irregularity and evidence of hyperandrogenism. While recognized since the 1800s, a clinical composite was not constructed until 1935 when Stein and Leventhal reported their findings of seven women with infertility, menstrual dysfunction, hirsutism, and enlarged ovaries. Notably, the ovaries contained numerous multiple cysts and the ovarian capsule was thickened. At the time, this preciseness of definition was sufficient to entitle the entity Stein-Leventhal syndrome. Subsequently, over the intervening years as investigators attempted to unĀ­ ravel the pathophysiology and genesis of this disorder and the number of reported studies increased, there ensued a gradual and distinct terminologic conversion to polycystic ovary syndrome, which, whether intentional or not, connoted a less well-defined condition. Perhaps this is appropriately so, given the seemingly broadening spectrum of clinical presentations and the continuing debate over what constitutes peos. The expansive new knowledge about peos was discussed to a significant degree at an international symposium organized by Serono Symposia USA and held in Boston in the late spring of 1995. Ovarian physiology, including the fate of the follicular unit, was a central focus with several presentations on the genesis, growth, and death of ovarian cellular components. A discusĀ­ sion of the regulation of ovarian cell function was also highlighted and comprised a major portion of the program.

Table of contents (23 chapters)

  • Regulation of Ovulation Rate

    Spearow, Jimmy L.

    Pages 1-20

  • Dynamics of Follicle Development in the Human Ovary

    Gougeon, Alain

    Pages 21-36

  • The Molecular Basis of Ovarian Cell Death

    Tilly, Jonathan L. (et al.)

    Pages 37-50

  • Polycystic Ovary Syndrome (PCOS): The Possible Roles of Apoptosis in Human Granulosa Cells

    Yeh, John (et al.)

    Pages 51-70

  • Potential Role of the Renin-Angiotensin System in Polycystic Ovaries

    Naftolin, Frederick (et al.)

    Pages 71-88

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-4613-8483-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $139.00
price for USA
  • ISBN 978-1-4613-8485-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Polycystic Ovary Syndrome
Editors
  • R. Jeffrey Chang
Series Title
Serono Symposia USA
Copyright
1996
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York, Inc.
eBook ISBN
978-1-4613-8483-0
DOI
10.1007/978-1-4613-8483-0
Softcover ISBN
978-1-4613-8485-4
Edition Number
1
Number of Pages
XVII, 370
Topics