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Intercellular Signalling in the Mammary Gland

  • Book
  • © 1995

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Editors:
  1. Colin J. Wilde

    1. Hannah Research Institute, Ayr, Scotland, UK

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  2. Malcolm Peaker

    1. Hannah Research Institute, Ayr, Scotland, UK

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  3. Christopher H. Knight

    1. Hannah Research Institute, Ayr, Scotland, UK

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Table of contents (54 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Mammary Development: Growth and Growth Factors

    1. The Environment of the Mammary Secretory Cell

      • Christopher H. Knight
      Pages 1-11

    2. Role of Bovine Placental Lactogen in Intercellular Signalling during Mammary Growth and Lactation

      • Robert J. Collier, John C. Byatt, Michael F. McGrath, Philip J. Eppard
      Pages 13-24

    3. Expression of Hox Genes in Normal and Neoplastic Mouse Mammary Gland

      • Yael Friedmann, Charles W. Daniel
      Pages 25-33

    4. Local Signals for Growth Cessation and Differentiation in the Mammary Gland

      • Richard Grosse
      Pages 35-44

    5. Apoptosis in Mammary Gland Involution: Isolation and Characterization of Apoptosis-Specific Genes

      • Wolfgang Bielke, Guo Ke, Robert Strange, Robert Friis
      Pages 45-55

    6. The Role of erbB-Family Genes and Wnt Genes in Normal and Preneoplastic Mammary Epithelium, Studied by Tissue Reconstitution

      • Paul A. W. Edwards, Clare Abram, Susan E. Hiby, Christina Niemeyer, Trevor C. Dale, Jane M. Bradbury
      Pages 57-66

    7. V-erbB Induces Abnormal Patterns of Growth in Mammary Epithelium

      • Clare L. Abram, Jane M. Bradbury, Martin J. Page, Paul A. W. Edwards
      Pages 67-68

    8. Interplay between Epidermal Growth Factor Receptor and Estrogen Receptor in Progression to Hormone Independence of Human Breast Cancer

      • Ton van Agthoven, Lambert C. J. Dorssers
      Pages 69-70

    9. Effect of Plane of Nutrition on Mammary Gland Development in Prepubertal Goats

      • Christine E. Bowden, Karen Plaut, Rhonda L. Maple
      Pages 71-72

    10. Activation of Basic Fibroblast Growth Factor (bFGF) by Heparan Sulphate (HS)

      • Hai-Lan Chen, Philip S. Rudland, John A. Smith, David G. Fernig
      Pages 73-74

    11. High Density Culture of Immuno-Magnetically Separated Human Mammary Luminal Cells

      • Catherine Clarke, Paul Monaghan, Michael J. O’Hare
      Pages 75-76

    12. Molecular Analysis of the Effects of Oestradiol in an in vivo Model of Normal Human Breast Proliferation

      • Robert B. Clarke, Ian J. Laidlaw, Anthony Howell, Elizabeth Anderson
      Pages 77-78

    13. Juxtacrine Growth Stimulation of Mouse Mammary Cells in Culture

      • Ursula K. Ehmann, Michael S. C. Chen, Aldrin A. Adamos
      Pages 79-80

    14. Fibroblast Growth Factors in Mammary Development and Cancer

      • David G. Fernig, Roger Barraclough, Youqiang Ke, John A. Smith, Angela Platt-Higgins, Mark C. Wilkinson et al.
      Pages 81-82

    15. Evidence of Growth Factor Production by Sheep Myoepithelial and Alveolar Epithelial Cells: Potential for Autocrine/Paracrine Interactions

      • Isabel A. Forsyth, James A. Taylor, Maggy Villa, R. Stewart Gilmour
      Pages 83-84

    16. Derivation of Conditionally Immortal Mammary Cell Lines

      • Katrina E. Gordon, Bert Binas, A. John Clark, Christine J. Watson
      Pages 85-85

    17. Effect of Relaxin on Primary Cultures of Goat Mammary Epithelial Cells

      • Sylvia Kondo, Colin J. Wilde, Gillian D. Bryant-Greenwood, Eleanor Taylor, Malcolm Peaker, Lynn M. Boddy-Finch
      Pages 87-88

    18. Differential Effects of Growth Factors Acting by Autocrine and Paracrine Pathways in Breast Cancer Cells

      • Anna Perachiotti, Philippa D. Darbre
      Pages 89-90

    19. Validation of Transforming Growth Factor ß-1 Binding Assay for Bovine Mammary Tissue

      • Karen Plaut, Rhonda L. Maple, Anthony V. Capuco, Alan W. Bell
      Pages 91-92
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About this book

All being done, we went to Mrs Shipmans, who is a great butter-woman; and I did see there the most of milke and cream, and the cleanest, that I ever saw in my life (29 May 1661). Among others, Sir Wm. Petty did tell me that in good earnest, he hath in his will left such parts of his estate to him that could invent such and such things -as among others, that could discover truly the way of milk coming into the breasts of a woman ... (22 March 1665). My wife tells me that she hears that my poor aunt James hath had her breast cut off here in tow- her breast having long been out of order (5 May 1665). From the Diary of Samuel Pepys, published as The Shorter Pepys (edited by R. Latham), Penguin Books (1987) The long-standing ultimate importance of research on the mammary gland is illustrated by the importance attached to cows' milk for human consumption, to human lactation and to breast cancer by Samuel Pepys and his contemporaries in the middle of the 17th century. Research has tended to develop in isolation in these three areas of continuing contemporary importance largely because in most countries, the underlying science of agricultural productivity is funded separately from the underlying science of human health and welfare.

Editors and Affiliations

  • Hannah Research Institute, Ayr, Scotland, UK

    Colin J. Wilde, Malcolm Peaker, Christopher H. Knight

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