Sex-Steroid Interactions with Growth Hormone

1. Front Matter

   Pages i-xxi

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2. Clinical Impact of Sex Steroids on Growth Hormone Secretion

   1. Front Matter

      Pages 1-1

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   2. Sex-Steroid—Growth Hormone Axis Interactions in Normal Female Puberty

      • Fernando Cassorla, Rossana Romńn

      Pages 3-10

   3. Sex-Steroid-Growth Hormone Interactions During Normal Male Puberty

      • Lisa D. Houchin, Alan D. Rogol

      Pages 11-19

   4. Impact of Testosterone Replacement on the Maturation of the Growth Hormone—IGF-I Axis

      • Andrea Giustina, Paolo Desenzani, Tiziano Scalvini

      Pages 20-31

   5. Sex-Steroid—Hormone Modulation of the Somatotropic Axis During Normal Male Puberty

      • Daniel L. Metzger, James R. Kerrigan

      Pages 32-43

   6. Influence of Testosterone on the GH—IGF-I Axis in Healthy Elderly Men

      • Marc R. Blackman, Colleen Christmas, Thomas Muüzer, Kieran G. O’Connor, Thomas E. Stevens, Michele F. Bellantoni et al.

      Pages 44-53

   7. Effect of Estrogen on GH Secretion and Action in Postmenopausal Women

      • Ken K. Y. Ho, Anthony J. O’Sullivan

      Pages 54-66

   8. Menstrual Cycle Interaction with the Growth Hormone Axis

      • Per Ovesen, Nina Vahl, Jens Sandahl Christiansen, Johannes D. Veldhuis, Jens Otto Lunde Jorgensen

      Pages 67-73

   9. Growth Hormone Axis Response to Superovulation

      • Bruce R. Carr

      Pages 74-81

   10. Androgenic Modulation of the Growth Hormone—IGF Axis and Its Impact on Metabolic Outcomes

       • David A. Fryburg, Arthur L. Weltman, Linda A. Jahn, Judy Y. Weltman, Eugene Samojlik, Raymond L. Hintz et al.

       Pages 82-92

   11. Proposed Mechanisms of Sex-Steroid— Hormone Neuromodulation of the Human GH—IGF-I Axis

       • Johannes D. Veldhuis, William S. Evans, Nikhita Shah, E. Shannon Story, Megan J. Bray, Stacey M. Anderson

       Pages 93-121

   12. The Growth Hormone Axis in Precocious Puberty

       • Paul A. Boepple

       Pages 122-130

3. Sex Steroids and GHRH-Somatostatin

   1. Front Matter

      Pages 131-131

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   2. Hypothalamic Control Mechanisms of Sexually Dimorphic Growth Hormone Secretory Patterns in the Rat

      • Gloria S. Tannenbaum

      Pages 133-143

   3. Sex Differences in Growth Hormone-Releasing Hormone (GHRH) and Somatostatin Neurons

      • Donald K. Clifton, Robert A. Steiner

      Pages 144-152

   4. Sex-Steroid Interaction with Somatostatin and GHRH in the Rat

      • Franco Sanchez-Franco, Fernando Pazos, Gumersindo Fernandez, Judith Lopez, Nuria Palacios, Lucinda Cacicedo

      Pages 153-159

   5. Sex-Steroid Effects on Primate Somatotrophs Kenneth C. Copeland

      • Johannes D. Veldhuis, Andrea Giustina

      Pages 160-171

   6. Sex-Steroid Effects on Perifused Pituitary

      • Richard J. Krieg Jr., Paul M. Martha Jr., James R. Kerrigan, Judy M. Batson, Timothy E. Sayles, Steven J. Kraus et al.

      Pages 172-182

   7. Somatotrope Heterogeneity and Its Involvement in Growth Hormone (GH) Regulation

      • Justo Pastor CastaÑo, José Luis Ramírez, José Carlos Garrido-Gracia, Francisco Gracia-Navarro

      Pages 183-191

Sex-Steroid Interactions with Growth Hormone presents the proceedings of an international symposium held from October 22-25 in Naples, Florida. The proceedings provide new insights and concepts gained by molecular, cellular and neuroendocrine research into mechanistic interactions of the reproductive and somatotrophic axes. Chapters include discussions of the impact of sex steroids on growth hormone secretion in both children and adults; sex steroids, growth hormone releasing factor, and somatostatin; how sex steroids modulate growth hormone action on target issues; and differential effects of growth hormone secretagogues in men and women. This volume is designed for physicians, scientists and other health professionals interested or trained in clinical and basic endocrinology, growth or reproduction.

• endocrinology
• estrogen receptor
• growth
• growth hormone
• hormone
• hormone therapy
• intracellular signaling
• metabolism
• puberty
• reproduction
• steroid
• steroids
• tissue

• Division of Endocrinology, Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, USA

  Johannes D. Veldhuis

• Endocrine Section Department of Internal Medicine, University of Brescia, Brescia, Italy

  Andrea Giustina

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