Molecular and Integrative Toxicology

Trichloroethylene: Toxicity and Health Risks

Editors: Gilbert, Kathleen M, Blossom, Sarah J (Eds.)

  • A comprehensive overview of documented and predicted health effects of trichloroethylene exposure
  • Explains how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases
  • Discusses the role of epigenetic alterations in trichloroethylene toxicity providing important mechanistic information, it may also provide and the basis for research on intervention therapy
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-4471-6311-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4471-6310-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4471-7241-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

A comprehensive overview of the effects of trichloroethylene toxicity caused by real-life exposure levels highlighting how exposure to trichloroethylene may contribute to the etiology of several idiopathic human diseases. Discussion will focus on different kinds of modeling and how they may be used to predict functional consequences and to dissect the contribution of different mechanistic pathways, including potential mechanisms of action for trichloroethylene toxicity in different organ systems. It will explore the role of epigenetic alterations in trichloroethylene toxicity, this provides important mechanistic information and may also provide the basis for intervention therapy. Chapters will also explain how the risks from trichloroethylene exposure may be greater in certain populations based on genetic predisposition, age of exposure and co-exposure to other chemicals With contributions from international experts in the field, Trichloroethylene: Toxicity and Health Risks is an essential resource for researchers and clinicians in toxicology, immunology, medicine and public health as well as industry and government regulatory scientists involved in safety and health protection and epidemiologists, highlighting the need for interdisciplinary cooperation in solving issues of environmental toxicity.

Table of contents (11 chapters)

  • History of TCE

    Doherty, Richard E.

    Pages 1-14

  • Trichloroethylene and Autoimmunity in Human and Animal Models

    Gilbert, Kathleen M.

    Pages 15-35

  • Hypersensitivity Dermatitis and Hepatitis

    Kamijima, Michihiro (et al.)

    Pages 37-52

  • Trichloroethylene-Induced Oxidative Stress and Autoimmunity

    Khan, M. Firoze (et al.)

    Pages 53-71

  • Brain and Behavioral Changes in Rodent Models

    Bale, Ambuja S.

    Pages 73-90

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4471-6311-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4471-6310-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4471-7241-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Trichloroethylene: Toxicity and Health Risks
Editors
  • Kathleen M Gilbert
  • Sarah J Blossom
Series Title
Molecular and Integrative Toxicology
Copyright
2014
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London
eBook ISBN
978-1-4471-6311-4
DOI
10.1007/978-1-4471-6311-4
Hardcover ISBN
978-1-4471-6310-7
Softcover ISBN
978-1-4471-7241-3
Series ISSN
2168-4219
Edition Number
1
Number of Pages
X, 245
Number of Illustrations and Tables
10 b/w illustrations, 13 illustrations in colour
Topics