An Introduction to Toxicology

Authors: Burcham, Philip C.

  • A readable yet up-to-date volume to introduce the discipline of toxicology
  • Illustrations that “unpack” the concepts being discussed in the text
  • The author is an academic researcher with extensive teaching experience at undergraduate and graduate level
see more benefits

Buy this book

eBook $69.99
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-1-4471-5553-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $89.99
price for USA
valid through November 5, 2017
  • ISBN 978-1-4471-5552-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $89.99
price for USA
valid through November 5, 2017
  • ISBN 978-1-4471-7256-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this Textbook

This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​

 

About the authors

After undergraduate majors in chemistry and pharmacology, Phil Burcham completed a PhD in biochemical toxicology in 1990 under the supervision of Dr Andrew W Harman at the University of Western Australia. He then completed postdoctoral training in molecular toxicology under Lawrence J Marnett at Vanderbilt University. After teaching pharmacology and toxicology at the University of Adelaide for 12 years he returned to Perth to establish a research group focused on studying noxious smoke constituents. His research efforts have led to 55 scientific publications. He has over 20 years experience in teaching toxicology, pharmacology and drug metabolism to science, medicine, pharmacy, podiatry and dentistry students.  His popular team-taught freshers course, Drugs that Changed the World, attracts over 400 enrolments. He currently serves on the Editorial Advisory board of Chemical Research in Toxicology and the Editorial Board of Toxicological Sciences.  He is also a member of the toxicology subsection of the Faculty of 1000 (Biology).

Reviews

From the book reviews:

“I found this to be an excellent text book, in fact one of the best I have referred to in recent times. Whether one is a non-toxicologist seeking an overview of the subject or an Industrial Toxicologist working every day to tackle the issues of product development, there is something for everybody. … This book should be a point of reference for any modern toxicologist – it will be for me!” (Jim Ridings, bts News Magazine of The British Toxicology Society, Vol. 1 (2), September, 2014)


Table of contents (10 chapters)

  • The Emergence of Modern Toxicology

    Burcham, Philip C.

    Pages 1-27

  • Core Concepts in Toxicology

    Burcham, Philip C.

    Pages 29-51

  • Toxicokinetics: The Behaviour of Chemicals in the Body

    Burcham, Philip C.

    Pages 53-90

  • Toxicodynamics: How Chemicals Harm Cells

    Burcham, Philip C.

    Pages 91-125

  • Fight Back: Adaptive Responses to Toxicant Exposure

    Burcham, Philip C.

    Pages 127-149

Buy this book

eBook $69.99
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-1-4471-5553-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $89.99
price for USA
valid through November 5, 2017
  • ISBN 978-1-4471-5552-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $89.99
price for USA
valid through November 5, 2017
  • ISBN 978-1-4471-7256-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
An Introduction to Toxicology
Authors
Copyright
2014
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London
Distribution Rights
Distribution rights for India: Researchco Book Centre, New Delhi, India
eBook ISBN
978-1-4471-5553-9
DOI
10.1007/978-1-4471-5553-9
Hardcover ISBN
978-1-4471-5552-2
Softcover ISBN
978-1-4471-7256-7
Edition Number
1
Number of Pages
XVI, 327
Number of Illustrations and Tables
92 b/w illustrations, 1 illustrations in colour
Topics