Physiological Assessment of Coronary Stenoses and the Microcirculation

Editors: Escaned, Javier, Davies, Justin (Eds.)

  • ​​Provides a clear and comprehensive review of the principles of coronary physiology
  • Gives a detailed description of available techniques for physiological assessment of coronary circulation in the catheterisation laboratory
  • Addresses the needs of clinicians and researchers working in the field of coronary artery disease for treating patients in their clinical practice ​
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eBook $139.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-1-4471-5245-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-4471-5244-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

​Since the introduction of coronary angiography, a key technique in understanding coronary artery disease, a number of paradigms regarding its study and interpretation have taken place. Following an emphasis on improved angiographic and subsequent intracoronary imaging techniques, functional assessment of coronary circulation has demonstrated to have major implications for diagnosis and treatment of coronary artery disease.  Fractional flow reserve, a pressure derived index of stenosis severity, constitutes the best example of the current importance of physiological assessment in clinical practice. However, the acceptance of FFR by cardiologists contrasts with important voids in knowledge on the basic principles of coronary physiology and of other available techniques that, as an alternative to FFR, allow a more comprehensive assessment of coronary circulation. This is particularly noticeable in the assessment of microcirculation, an unavoidable compartment of coronary circulation that is frequently affected in acute coronary syndromes of in the presence of cardiovascular risk factors or non-coronary heart disease. A deeper understanding of the relationship between epicardial vessel and microcirculatory involvement has started with the advent of newer imaging techniques like invasive optical coherence tomography, and non-invasive CT and NMR techniques. This book aims to be an indispensable tool for clinicians and researches in the field of coronary artery disease. It provides a balanced, comprehensive review of anatomy, physiology and available techniques, discusses both the diagnosis of epicardial vessel and microcirculatory disease, the impact of different diseases at different levels of coronary circulation, and the best way to address a separate or combined assessment of different levels of coronary circulation.  ​

About the authors

Javier Escaned MD PhD FESC is Head of Section (Interventional Cardiology) at Hospital Clinico 

San Carlos, and Associate Professor of Medicine at Complutense University (Madrid, Spain). He 

trained as a cardiologist the United Kingdom (Queen Elizabeth University Hospital, Birmingham 

and Walsgrave Hospital, Coventry) before moving to the Thoraxcenter / Rotterdam (The 

Netherlands), where he obtained his PhD degree in 1994. He is author of more than 250 scientific 

articles, books and book chapters on different aspects of interventional cardiology, imaging and 

physiology. He is co-editor with Patrick Serruys of the textbook “Coronary Stenosis. Imaging, 

Structure and Physiology”, whose new edition was launched in May 2015. Current positions in 

scientific societies include: board member (treasurer) of European Association of Percutaneous 

Cardiovascular Interventions (EAPCI), nucleus member of the ESC Working Group on 

Pathophysiology and Microcirculation, and co-director of EuroPCR. In 2014 he served as director of 

the ESC International Summit on Coronary Microcirculation and Heart Disease. Recent or on-going 

international multicentre trials in which he has a principal investigator role include: ADVISE II, 

SYNTAX II, PILOT SECRET, SHEAR STENT and DEFINE-FLAIR. Some of his additional 

interests are philosophy, education and music. 



Table of contents (22 chapters)

  • Hemodynamic Effects of Epicardial Stenoses

    Casadonte, Lorena (et al.)

    Pages 3-18

  • Atherogenesis: The Development of Stable and Unstable Plaques

    Mori, Hiroyoshi (et al.)

    Pages 21-37

  • Microcirculatory Dysfunction

    Hoeven, Nina W. (et al.)

    Pages 39-53

  • Remodeling of Epicardial Coronary Vessels

    Gonzalo, Nieves (et al.)

    Pages 55-63

  • Collateral Circulation

    Seiler, Christian

    Pages 65-77

Buy this book

eBook $139.00
price for USA (gross)
valid through November 5, 2017
  • ISBN 978-1-4471-5245-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-4471-5244-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Physiological Assessment of Coronary Stenoses and the Microcirculation
Editors
  • Javier Escaned
  • Justin Davies
Copyright
2017
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London
eBook ISBN
978-1-4471-5245-3
DOI
10.1007/978-1-4471-5245-3
Hardcover ISBN
978-1-4471-5244-6
Edition Number
1
Number of Pages
XIII, 313
Number of Illustrations and Tables
27 b/w illustrations, 131 illustrations in colour
Topics