Ankylosing spondylitis and Klebsiella

Authors: Ebringer, Alan

  • Ankylosing spondylitis and Klebsiella is a handy and informative text on the cause of Ankylosing spondylitis
  • Contains full color illustrations and depicts the microbe Klebsiella’s action on the body
  • Ankylosing spondylitis and Klebsiella is a valuable information resource which contains all of the latest research on the subject making it accessible to patients, research institutions, pharmaceutical firms, universities, health professionals and the general public
  • Contains descriptions of antibodies to Klebsiella in AS patients from 15 different countries
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eBook $169.00
price for USA (gross)
  • ISBN 978-1-4471-4300-0
  • Digitally watermarked, DRM-free
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  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4471-4299-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
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About this book

Ankylosing spondylitis and Klebsiella is a comprehensive and informative text on the cause of Ankylosing spondylitis. Ankylosing spondylitis (AS) is a condition which affects 20 million people worldwide and is likely caused or initiated by a bowel infection from Klebsiella bacteria.

 

When a patient is infected by Klebsiella bacteria, his or her immune system will make antibodies against all the antigens or molecules found in the microbe. Because some of the bacterial antigens resemble self tissues, the anti-bacterial antibodies will attack not only the bacteria but also the self tissues such as the joints and the cells having the same HLA molecules, which is how the disease AS starts.  This is the concept of molecular similarity or “molecular mimicry” which previously has been found to work in two other autoimmune diseases; rheumatic fever and rheumatoid arthritis.

 

The first paper on this subject was published in 1976 and since then over 100 papers on rheumatological topics have been published, from Prof Ebringer’s group, at the Division of Life Sciences, King’s College in London, UK.

 

The relevant information from these papers is extracted and presented in this book format making it accessible to health professionals, research institutions, pharmaceutical companies and universities and the general public.

Table of contents (22 chapters)

  • Ankylosing Spondylitis as a Scientific Problem

    Ebringer, Alan (et al.)

    Pages 1-6

  • History of the Origin of Ankylosing Spondylitis

    Ebringer, Alan (et al.)

    Pages 7-13

  • The Discovery of HLA-B27 in Ankylosing Spondylitis and Related Disorders

    Ebringer, Alan (et al.)

    Pages 15-21

  • Molecular Mimicry Between HLA-B27 and Klebsiella Bacteria Investigated by Using Rabbit Antisera

    Ebringer, Alan (et al.)

    Pages 23-33

  • Molecular Mimicry Between HLA-B27 and Klebsiella Bacteria Investigated by Using Human Tissue Typing Sera

    Ebringer, Alan (et al.)

    Pages 35-43

Buy this book

eBook $169.00
price for USA (gross)
  • ISBN 978-1-4471-4300-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.00
price for USA
  • ISBN 978-1-4471-4299-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Ankylosing spondylitis and Klebsiella
Authors
Copyright
2013
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London
eBook ISBN
978-1-4471-4300-0
DOI
10.1007/978-1-4471-4300-0
Hardcover ISBN
978-1-4471-4299-7
Edition Number
1
Number of Pages
XX, 256
Topics