Osteoimmunopathology

Evidence-Based Perspectives from Molecular Biology to Systems Biology

Authors: Chiappelli, Francesco

  • First work to provide sound overview of emerging field of Osteoimmunology
  • Arises from evidence that the skeletal system and the immune system are intimately intertwined
  • Tables and drawings illustrate complex concepts
see more benefits

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4419-9495-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4419-9494-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4899-9946-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Osteoimmunology pertains to the study of the relationship between the bones, particularly the bone marrow, and the immune system.   This monograph pursues the best available evidence, by means of research synthesis, for the characterization of the physiological relevance and pathological implications of the inter-connectedness between the skeletal and the immune system.  Research will be discussed that highlights the associated role of the circulatory, nervous and endocrine systems, as well as proteomic and genomic pathways and signatures. Emphasis is given that domain of medicine that relates to the oral cavity, its diseases and their systemic sequelae.

This monograph arises from observations that have suggested that the skeletal system and the immune system are intimately intertwined. Chronic inflammatory reactions subsequent to an excessive immune reaction can damage the bones, as in rheumatoid arthritis (RA), osteoporosis, patients seropositive for the human immunodeficiency virus (HIV)-1 and with signs and sympotoms of the acquired immune deficiency syndrome (AIDS), and bone cancer. Bones – in particular the bone marrow – are one of the primary locations in which cells of the immune system mature.

In brief, this monograph begins to answer a range of  questions, such as, what is osteoimmunology all about?, does the immune system and its components affect bone development?, how do stress hormones impact upon the pathophysiology of bone-immune interactions?, can the scientific process of research synthesis, obtain the best available evidence for treatment of diseases involving the bone-immune entity (i.e., osteoimmunopathologies) means of evidence-based clinical decision-making directed at the treatment of osteoimmune pathologies?

Table of contents (4 chapters)

  • Osteoimmunology: The Bone-Immune Crosstalk

    Chiappelli, Francesco

    Pages 1-37

  • Osteoimmunopathology

    Chiappelli, Francesco

    Pages 39-67

  • Translational Evidence-Based Interventions in Osteoimmunology

    Chiappelli, Francesco

    Pages 69-100

  • Summary and Conclusion

    Chiappelli, Francesco

    Pages 101-102

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-4419-9495-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-4419-9494-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-1-4899-9946-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Osteoimmunopathology
Book Subtitle
Evidence-Based Perspectives from Molecular Biology to Systems Biology
Authors
Copyright
2011
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-9495-0
DOI
10.1007/978-1-4419-9495-0
Hardcover ISBN
978-1-4419-9494-3
Softcover ISBN
978-1-4899-9946-7
Edition Number
1
Number of Pages
XII, 137
Topics