Overview
- Editors:
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Nigel M. Hooper
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University of Leeds, Leeds, UK
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Uwe Lendeckel
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Otto-von-Guericke University, Magdeburg, Germany
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Table of contents (14 chapters)
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- Michael W. Thompson, Louis B. Hersh
Pages 1-15
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- Joseph A. Vetro, Benjamin Dummitt, Yie-Hwa Chang
Pages 17-44
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- Seiji Nomura, Tomomi Ito, Shigehiko Mizutani
Pages 45-59
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- Siew Yeen Chai, Ruani Fernando, Siying Ye, Grantley R. Peck, Anthony L. Albiston
Pages 61-81
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- Fredrik Tholander, Anders Wetterholm, Jesper Z. Haeggström
Pages 83-112
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- Sandrine Cadel, Christophe Piesse, Cécile Gouzy-Darmon, Paul Cohen, Thierry Foulon
Pages 113-126
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- Tomo Saric, Alfred L. Goldberg
Pages 145-178
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- Nenad Petrovic, Wolfgang Schacke, Linda H. Shapiro
Pages 179-200
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- Uwe Lendeckel, Alicja Bukowska, Jens Holger Lättig, Wolfgang Brandt
Pages 201-227
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- Xavier Iturrioz, Annabelle Reaux, Le Goazigo, Catherine Llorens-Cortes
Pages 229-250
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- Giuseppe Molinaro, Guy Boileau, Albert Adam
Pages 251-269
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- Oscar A. Scornik, Violeta Botbol
Pages 271-307
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- Darren R. Brooks, R. Elwyn Isaac
Pages 309-329
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Back Matter
Pages 331-336
About this book
Aminopeptidases in Biology and Disease provides a comprehensive review of the emerging role of aminopeptidases in a range of biological processes and disease situations. Processes as diverse as angiogenesis, antigen presentation, neuropeptide and hormone processing, pregnancy and reproduction, protein turnover, memory, inflammation, tumour growth, cancer and metastasis, blood pressure and hypertension all critically involve one or more aminopeptidases. The individual chapters have been written by experts in the field who have provided detailed accounts of the central roles played by various aminopeptidases in biology and disease.
Editors and Affiliations
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University of Leeds, Leeds, UK
Nigel M. Hooper
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Otto-von-Guericke University, Magdeburg, Germany
Uwe Lendeckel
About the editors
Nigel Hooper is Professor of Biochemistry in the School of Biochemistry and Molecular Biology at the University of Leeds, UK. He received his Ph.D in 1984 from the University of Leeds with a thesis on the "Metabolism of Neuropeptides by Cell-surface Peptidases" which stimulated his interest in proteases and paved the way for much of his subsequent research. He currently co-leads the Proteolysis Research Group at Leeds and among other topics, continues to study the structure and function of several cell-surface proteases, with a particular interest in their mode of attachment to the membrane. He has published over 90 research papers, edited 4 books and co-authored the widely acclaimed undergraduate textbook Instant Notes Biochemistry.
Uwe Lendeckel is a Reader at the Institute of Experimental Internal Medicine at the Otto-von-Guericke University of Magdeburg, Germany. After his study of pharmacology and toxicology he received his Ph.D in biochemistry in 1990 from the Ernst-Moritz-Arndt University of Greifswald. His thesis on the "expression of the pro-opiomelanocortin gene in rat Islets of Langerhans and other tissues" stimulated his interest in the neuro-immunological cross-talk and the regulatory roles of cell surface proteases therein. In 1989 he joined the ectopeptidase research group at the University of Magdeburg and since then continues to study regulation of expression and the function of T cell ectopeptidases in the normal and pathological immune response, with special focus on the membrane alanyl-aminopeptidase. He has published over 40 research papers.
