Protein Reviews

Folding of Disulfide Proteins

Editors: Chang, Rowen J. Y., Ventura, Salvador (Eds.)

  • Covers the knowledge of protein folding accumulated from studies of disulfide-containing proteins, including methodologies, folding pathways, and folding mechanism of numerous extensively characterized disulfide proteins.
  • Valuable supplementary reading for general biochemistry, biophysics, molecular biology, and cellular biology courses for graduate and undergraduate students.
  • Can be used for specialized graduate-level biochemistry, biophysics, and molecular biology courses dedicated to protein folding as well as related biological problems and diseases.
see more benefits

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-1-4419-7273-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-1-4419-7272-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-1-4614-2997-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Disulfide-containing proteins belong to a unique class of proteins for studying the mechanism of protein folding. Their folding mechanism can be analyzed by three distinct techniques: (1) The conventional denaturation-renaturation method (disulfide intact); (2) The disulfide oxidation method (oxidative folding); and (3) The emerging disulfide scrambling method. Each technique provides specific information as to how an unfolded disulfide protein refolds to form the native structure. This book is intended to highlight the knowledge of several important proteins (BPTI, RNase A, beta-Lactalbumin and Lysozyme etc.) that have been characterized in depth by these methodologies. The book will also devote sections to comparing these methodologies and chaperones (PDI and Dsb machineries) that facilitate folding of disulfide proteins.

Folding of Disulfide Proteins aims to cover the knowledge of protein folding accumulated from studies of disulfide-containing proteins, including methodologies, folding pathways, and folding mechanism of numerous extensively characterized disulfide proteins. This book will be of interest to those interested in problems related to protein folding, and anyone who is interested in understanding the mechanism of protein misfolding and protein misfolding-related diseases.

Folding of Disulfide Proteins aims to cover the knowledge of protein folding accumulated from studies of disulfide-containing proteins, including methodologies, folding pathways, and folding mechanism of numerous extensively characterized disulfide proteins. This book will be of interest to those interested in problems related to protein folding, and anyone who is interested in understanding the mechanism of protein misfolding and protein misfolding-related diseases.

Table of contents (11 chapters)

  • Oxidative Folding: Coupling Conformational Folding and Disulfide Formation

    Ventura, Salvador (et al.)

    Pages 1-22

  • The Case of Oxidative Folding of Ribonuclease A: Factors Impacting Fold Maturation of ER-Processed Proteins

    Narayan, Mahesh

    Pages 23-42

  • Cystine Knot Folding in Cyclotides

    Daly, Norelle L. (et al.)

    Pages 43-61

  • In Vitro Folding of Single/Double Chain Insulins and Related Proteins

    Feng, You-Min

    Pages 63-89

  • Unfolding and Refolding of Disulfide Proteins Using the Method Disulfide Scrambling

    Chang, Rowen J. Y.

    Pages 91-108

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-1-4419-7273-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-1-4419-7272-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-1-4614-2997-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Folding of Disulfide Proteins
Editors
  • Rowen J. Y. Chang
  • Salvador Ventura
Series Title
Protein Reviews
Series Volume
14
Copyright
2011
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-7273-6
DOI
10.1007/978-1-4419-7273-6
Hardcover ISBN
978-1-4419-7272-9
Softcover ISBN
978-1-4614-2997-5
Edition Number
1
Number of Pages
X, 286
Topics