Endocrine Updates

Obesity Before Birth

Maternal and prenatal influences on the offspring

Editors: Lustig, Robert (Ed.)

  • Contributes to a resolution of the nature-nurture controversy
  • Provides guidance to clinical practitioners involved in both prenatal and postnatal care
  • Further stimulates research into the underlying mechanisms as well as the prevention and treatment of this phenomenon
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eBook $229.00
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  • ISBN 978-1-4419-7034-3
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Hardcover $289.00
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  • ISBN 978-1-4419-7033-6
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Softcover $289.00
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  • ISBN 978-1-4614-2686-8
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About this book

Obesity obeys the First Law of Thermodynamics. The routine assumption is that obesity is the result of a mismatch between calories in and calories out; in other words, the result of two divergent behaviors. However, there is mounting evidence that biochemical forces can drive obligate weight gain, and that the observed behaviors of increased energy intake and decreased energy expenditure are secondary to these processes. Furthermore, many of these biochemical forces are determined in utero; resulting in a developmental drive toward obesity and disease in later life. Four distinct prenatal forces have thus far been identified: 1) genetics; 2) epigenetics; 3) developmental programming; and 4) environmental obesogens. This volume explores the evidence for each of these in detail in human and animal models, and attempts to provide a cohesive analysis of the biochemical bases of obesity. This volume will appeal to geneticists, developmental biologists, endocrinologists, epidemiologists, toxicologists, obstetrician/gynecologists, nutritionists, veterinary scientists, animal husbandry researchers, domestic species researchers, and obesity researchers and practitioners. "This very timely volume provides an in-depth scholarly overview of a critical challenge facing our society—the obesity epidemic. Dr. Robert H. Lustig has assembled expert authors to address the fundamental contribution of preprogrammed genetic disorders leading to obesity, as well as the role of very early environmental influences. The chapters range from classic genetic mechanistic understanding through intra-uterine epigenetic influences, factors determining developmental programming, and the new clinical science of perinatal obesogens. Obesity Before Birth: Maternal and prenatal influences on the offspring, brings easily accessible, cutting edge information to geneticists, pediatricians, endocrinologists, as well as those clinicians and scientists pursuing the complex yet elusive causes of childhood obesity and related disorders." - Shlomo Melmed, M.D. Series Editor

Reviews

From the reviews:

“An interesting and timely book. … For obstetricians, neonatologists and pediatricians in general. Recommended.” (Pediatric Endocrinology Reviews (PER), Vol. 9 (2), December, 2011)


Table of contents (19 chapters)

  • Obesity: Nature or Nurture?

    Lustig, Robert H.

    Pages 1-22

  • The Contribution of Heredity to Clinical Obesity

    Andersson, Johanna C. (et al.)

    Pages 25-52

  • Monogenic Disorders Within the Energy Balance Pathway

    Aslan, Ivy R. (et al.)

    Pages 53-69

  • Ciliary Syndromes and Obesity

    Parker, David S. (et al.)

    Pages 71-93

  • Genome-Wide Association Studies and Human Population Obesity

    Loos, Ruth J.F. (et al.)

    Pages 95-112

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4419-7034-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4419-7033-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4614-2686-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Obesity Before Birth
Book Subtitle
Maternal and prenatal influences on the offspring
Editors
  • Robert Lustig
Series Title
Endocrine Updates
Series Volume
30
Copyright
2011
Publisher
Springer US
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-7034-3
DOI
10.1007/978-1-4419-7034-3
Hardcover ISBN
978-1-4419-7033-6
Softcover ISBN
978-1-4614-2686-8
Series ISSN
1566-0729
Edition Number
1
Number of Pages
XIV, 414
Topics