Advances in Neurobiology

Cytoskeleton of the Nervous System

Editors: Nixon, Ralph A., Yuan, Aidong (Eds.)

  • 1. Describes cytoskeleton in axonal development and pathology, microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic protein 2. Focuses on functional significance of neuronal cytoskeleton in axonal transport 3. Encourages further development of unifying principles, stimulates new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease

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Hardcover $479.00
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About this book

Without a cytoskeleton, a neuron or glial cell would be a shapeless jelly mass unable to function in the milieu of the brain. If we are to understand neuronal cells function in health and disease, we must determine how the cytoskeleton forms and contributes to neural physiology and pathobiology. Cytoskeleton of the Nervous System provides a comprehensive, authoritative and up-to-date account of what we now know and what we want to know in the near future--about the functioning of the cytoskeleton of neuronal cells at the molecular level. In lively accounts, which are unafraid to address controversy, Cytoskeleton of the Nervous System introduces readers to the most sophisticated concepts and latest discoveries: from overexpression systems to knock-out models for specific cytoskeletal proteins, from continuous transport assays in vivo to live-cell imaging in primary neurons, and from factors regulating cytoskeleton behavior to the dysregulation of these processes leading to neurological disease.

About the authors

Ralph A. Nixon is the Director of Silberstein Institute and Center of Excellence on Brain Aging; a Professor of Psychiatry and Cell Biology at NYU Langone Medical Center; the Director of Research and The Center for Dementia Research at Nathan S. Kline Institute for Psychiatric Research. Aidong (David) Yuan is the Research Project Manager at the Center for Dementia Research, Nathan S. Kline Institute; a Research Assistant Professor of Psychiatry at New York University Langone Medical Center and New York University School of Medicine.

Table of contents (29 chapters)

  • Central Axonal Development and Pathology in Early Life

    Haynes, Robin L. (et al.)

    Pages 1-53

  • Microtubules in the Nervous System

    Fukushima, Nobuyuki

    Pages 55-71

  • Tau Phosphorylation

    Avila, Jesús (et al.)

    Pages 73-82

  • Tau Pathology

    Sergeant, Nicolas (et al.)

    Pages 83-132

  • Tauopathy and Brain Aging

    Takashima, Akihiko

    Pages 133-150

Buy this book

eBook $379.00
price for USA (gross)
  • ISBN 978-1-4419-6787-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $479.00
price for USA
  • ISBN 978-1-4419-6786-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cytoskeleton of the Nervous System
Editors
  • Ralph A. Nixon
  • Aidong Yuan
Series Title
Advances in Neurobiology
Series Volume
3
Copyright
2011
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-6787-9
DOI
10.1007/978-1-4419-6787-9
Hardcover ISBN
978-1-4419-6786-2
Series ISSN
2190-5215
Edition Number
1
Number of Pages
XV, 774
Topics