Design and Analysis of Biomolecular Circuits

Engineering Approaches to Systems and Synthetic Biology

Editors: Koeppl, H., Densmore, D., Setti, G., di Bernardo, M. (Eds.)

  • Provides a thorough overview of state of the art in synthetic and systems biology
  • Applies to biological systems the formal abstraction methods used to cope with the complexity of today’s electronic devices
  • First book to discuss the enabling CAD technologies in terms of data acquisition and DNA synthesis
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Hardcover $249.00
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  • ISBN 978-1-4899-9505-6
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About this book

This book is devoted to the design and analysis of biomolecular circuits as considered in systems biology and synthetic biology.  The aim of the book is to present in a coherent framework some of the most recent work on the analysis, simulation and design of biomolecular circuits and systems, reflecting the interdisciplinary and collaborative nature of the field. The results discussed range from how these systems should be modeled and analyzed, to how they should be physically designed and implemented.  

Drawing parallels to electronic circuit design, this book’s contents are organized to reflect what the editors believe are the important, necessary steps to build complex synthetic circuits.  Coverage includes analysis and simulation, modularity and abstraction, design and standardization, and enabling technologies. Each of these themes is organized in different chapters that are self-contained so that they can be read individually by experts but also read sequentially by someone wanting to get an overview of the field. This book is intended for computational scientists, e.g. mathematicians, physicists, computer scientist or engineers as well as for researchers from the life sciences. Every effort has been made to make the presentation accessible to a broad, multi-disciplinary audience.

Reviews

From the reviews:

“This collection of papers is an excellent reference for anyone who would like to learn more about the engineering and computing side of systems and synthetic biology. … this clear and detailed volume will help to introduce mathematicians, engineers, and computer scientists to an application of their fields in biology. It will also serve biologists who want to know more about how in silico technologies can be an important part of the arsenal used to understand and create biological systems.” (Sara Kalvala, ACM Computing Reviews, June, 2012)


Table of contents (17 chapters)

  • Continuous Time Markov Chain Models for Chemical Reaction Networks

    Anderson, David F. (et al.)

    Pages 3-42

  • Stochastic Simulation for Spatial Modelling of Dynamic Processes in a Living Cell

    Burrage, Kevin (et al.)

    Pages 43-62

  • Graph-Theoretic Analysis of Multistability and Monotonicity for Biochemical Reaction Networks

    Craciun, Gheorghe (et al.)

    Pages 63-72

  • From Structure to Dynamics in Biological Networks

    Banaji, Murad

    Pages 73-92

  • Contraction Theory for Systems Biology

    Russo, Giovanni (et al.)

    Pages 93-114

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-4419-6766-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-4419-6765-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-4899-9505-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Design and Analysis of Biomolecular Circuits
Book Subtitle
Engineering Approaches to Systems and Synthetic Biology
Editors
  • Heinz Koeppl
  • Douglas Densmore
  • Gianluca Setti
  • Mario di Bernardo
Copyright
2011
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-6766-4
DOI
10.1007/978-1-4419-6766-4
Hardcover ISBN
978-1-4419-6765-7
Softcover ISBN
978-1-4899-9505-6
Edition Number
1
Number of Pages
XIII, 402
Topics