Protein Reviews

Post-Translational Modifications in Health and Disease

Editors: Vidal, Cecilio J. (Ed.)

  • 1. Over 40 color figures
  • 2. Contains 19 updated reviews that stimulate further investigations in the proteomic field
  • 3. Improves current understanding of protein modifications, allowing new avenues to prevent and/or alleviate human and animal diseases
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eBook $269.00
price for USA (gross)
  • ISBN 978-1-4419-6382-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $339.00
price for USA
  • ISBN 978-1-4419-6381-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $339.00
price for USA
  • ISBN 978-1-4614-2700-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Post-translational modifications serve many different purposes in a wide variety of cellular processes,such as protein synthesis, folding, stability, the housing of prosthetic groups, vesicular trafficking,protein targeting to particular cell stores, exocytosis and endocytosis, the biogenesis of cell organelles and basal lamina. Signal transduction, with functional effects for enzyme regulation and metabolic control on the one hand, and gene expression, cell division, differentiation and apoptosis on the other, is also prominent. Post-translational Modifications in Health and Disease provides the reader with nineteen reviews that stimulate further investigations in the proteomic field - focusing on functional and pathological aspects of protein prenylation, the incorporation of glycosylphosphatidylinositol (GPI) moieties, oxidation, nitrosylation, glycosylation, and phosphorylation and dephosphorylation - with emphasis on their outcome for protein-protein interaction phenomena and down-stream effects. Additional chapters are devoted to protein ubiquitination, sumoylation and endoplasmic reticulum-associated degradation (ERAD), the influence of histone modification on gene expression and DNA repair, and proteolytic processing of intracellular and basal lamina proteins. This book will be of particular significance to researchers, clinicians, and students of biology, pharmacy and medicine.

Table of contents (19 chapters)

  • Isoprenoid Modifications

    Nguyen, Uyen T. T. (et al.)

    Pages 1-37

  • GPI-Anchored Proteins in Health and Disease

    Taylor, David R. (et al.)

    Pages 39-55

  • Protein Oxidation

    Quiney, C. (et al.)

    Pages 57-78

  • Involvement of S-Nitrosylation in Neurodegeneration

    Li, Yihang (et al.)

    Pages 79-95

  • Protein Glysosylation and Congenital Disorders of Glycosylation

    Morava, Eva (et al.)

    Pages 97-117

Buy this book

eBook $269.00
price for USA (gross)
  • ISBN 978-1-4419-6382-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $339.00
price for USA
  • ISBN 978-1-4419-6381-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $339.00
price for USA
  • ISBN 978-1-4614-2700-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Post-Translational Modifications in Health and Disease
Editors
  • Cecilio J. Vidal
Series Title
Protein Reviews
Series Volume
13
Copyright
2011
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-6382-6
DOI
10.1007/978-1-4419-6382-6
Hardcover ISBN
978-1-4419-6381-9
Softcover ISBN
978-1-4614-2700-1
Edition Number
1
Number of Pages
XIV, 490
Topics