Advances in Experimental Medicine and Biology

Inflammation and Retinal Disease: Complement Biology and Pathology

Editors: Lambris, John D., Adamis, Anthony P. (Eds.)

  • 1. Comprehensive look at the pathology and biology of retinal inflammation
  • 2. Written by current, respected opthamologists and eye researchers
  • 3. Reports on age-related degeneration, gene-associations, and other physiological pathways to retinal inflammation
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eBook $229.00
price for USA (gross)
  • ISBN 978-1-4419-5635-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4419-5634-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4614-2648-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Numerous studies have pointed to the key role of complement in the pathogenesis of retinal disease, particularly age-related macular degeneration (AMD). Reports about new gene associations and links to other physiological pathways are emerging almost on a weekly base. Several promising clinical candidates covering a wide area of potential treatment applications are in the pipelines of both industrial and academic groups. This indicates an increasing interest in complement as a therapeutic target. In view of these exciting discoveries, scientists from around the world convened at the 1st Aegean Conferences Conference on Inflammation and Retinal Disease: Complement Biology and Pathology (June 10-17, 2007) in Crete, Greece, to discuss recent advances in this rapidly-evolving field. This volume represents a collection of topics on the functions of complement in eye diseases, pathophysiology, protein structures, and complement therapeutics discussed during the conference.

Table of contents (11 chapters)

  • The Case for Complement and Inflammation in AMD: Open Questions

    Karagianni, Natalia (et al.)

    Pages 1-7

  • The Role of Complement in AMD

    Zipfel, Peter F. (et al.)

    Pages 9-24

  • Multiple Interactions of Complement Factor H with Its Ligands in Solution: A Progress Report

    Perkins, Stephen J. (et al.)

    Pages 25-47

  • Genetic Control of Complement Activation in Humans and Age Related Macular Degeneration

    Hecker, Laura A. (et al.)

    Pages 49-62

  • Bisretinoids of RPE Lipofuscin: Trigger for Complement Activation in Age-Related Macular Degeneration

    Sparrow, Janet R.

    Pages 63-74

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4419-5635-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4419-5634-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4614-2648-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Inflammation and Retinal Disease: Complement Biology and Pathology
Editors
  • John D. Lambris
  • Anthony P. Adamis
Series Title
Advances in Experimental Medicine and Biology
Series Volume
703
Copyright
2010
Publisher
Springer-Verlag New York
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-4419-5635-4
DOI
10.1007/978-1-4419-5635-4
Hardcover ISBN
978-1-4419-5634-7
Softcover ISBN
978-1-4614-2648-6
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIV, 170
Topics