Advances in Experimental Medicine and Biology

Structure and Function of the Neural Cell Adhesion Molecule NCAM

Editors: Berezin, Vladimir (Ed.)

  • Provides an introduction to current knowledge of extracellular and intracellular NCAM ligands and the structural basis of NCAM interactions with the fibroblast growth factor (FGF) receptor
  • Examines various aspects of NCAM structure and function, making for a straightforward approach to NCAM
  • Explores new therapeutic potential of NCAM mimetics
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eBook $229.00
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  • ISBN 978-1-4419-1170-4
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Hardcover $289.00
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  • ISBN 978-1-4419-1169-8
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Softcover $289.00
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  • ISBN 978-1-4614-2545-8
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About this book

Adhesive interactions are important for cell trafficking, differentiation, function and tissue formation. In the nervous system, many cell adhesion molecules (CAMs) are involved in migration of neuroblasts, outgrowth and fasciculation of neuronal processes, formation of synapses and rearrangements of synaptic contacts associated with plasticity including learning and memory. More than eighty CAMs were found to be localized at synaptic sites, where they in a regulated manner bridge pre- and postsynaptic specializations thereby modulating synaptic function. Structure and Function of the Neural Cell Adhesion Molecule NCAM describes recent developments concerning structural, functional and possible therapeutic aspects of one particular CAM, the neural cell adhesion molecule (NCAM). NCAM is one of the first identified and most studied CAMs, and this book is the first attempt to collectively summarize our current knowledge of this important cell adhesion molecule.

Table of contents (26 chapters)

  • Structural Biology of NCAM

    Soroka, Vladislav (et al.)

    Pages 3-22

  • Extracellular Protein Interactions Mediated by the Neural Cell Adhesion Molecule, NCAM: Heterophilic Interactions Between NCAM and Cell Adhesion Molecules, Extracellular Matrix Proteins, and Viruses

    Nielsen, Janne (et al.)

    Pages 23-53

  • Intracelluar Ligands of NCAM

    Büttner, Bettina (et al.)

    Pages 55-66

  • NCAM and the FGF-Receptor

    Kiselyov, Vladislav V.

    Pages 67-79

  • The Role of ATP in the Regulation of NCAM Function

    Hübschmann, Martin V. (et al.)

    Pages 81-91

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-4419-1170-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-4419-1169-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-4614-2545-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Structure and Function of the Neural Cell Adhesion Molecule NCAM
Editors
  • Vladimir Berezin
Series Title
Advances in Experimental Medicine and Biology
Series Volume
663
Copyright
2010
Publisher
Springer-Verlag New York
Copyright Holder
Springer-Verlag New York
eBook ISBN
978-1-4419-1170-4
DOI
10.1007/978-1-4419-1170-4
Hardcover ISBN
978-1-4419-1169-8
Softcover ISBN
978-1-4614-2545-8
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XVI, 434
Number of Illustrations and Tables
22 b/w illustrations, 45 illustrations in colour
Topics